Evidence mapPaperPMID 34177613Full record

ArticleFrontiers in physiology2021

Acute Effects on the Human Peripheral Blood Transcriptome of Decompression Sickness Secondary to Scuba Diving.

Kurt Magri, Ingrid Eftedal, Vanessa Petroni Magri, Lyubisa Matity, Charles Paul Azzopardi, Stephen Muscat, Nikolai Paul Pace

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  9. Review
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  11. The management of patent foramen ovale in divers: where do we stand?Therapeutic advances in neurological disorders · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kurt MagriHyperbaric Unit, Department of Medicine, Mater Dei Hospital, Msida, Malta.
Ingrid EftedalDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, NTNU Norwegian University of Science and Technology, Trondheim, Norway.
Vanessa Petroni MagriDepartment of Clinical Pharmacology and Therapeutics, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
Lyubisa MatityHyperbaric Unit, Department of Medicine, Mater Dei Hospital, Msida, Malta.
Charles Paul AzzopardiHyperbaric Unit, Department of Medicine, Mater Dei Hospital, Msida, Malta.
Stephen MuscatHyperbaric Unit, Department of Medicine, Mater Dei Hospital, Msida, Malta.
Nikolai Paul PaceCentre for Molecular Medicine and Biobanking, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
Mater Dei Hospital · MTUniversity of Malta · MTNorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decompression sickness (DCS) develops due to inert gas bubble formation in bodily tissues and in the circulation, leading to a wide range of potentially serious clinical manifestations. Its pathophysiology remains incompletely understood. In this study, we aim to explore changes in the human leukocyte transcriptome in divers with DCS compared to closely matched unaffected controls after uneventful diving. Cases (

Indexed as

decompression illnessdecompression sicknessimmediate early genesleukocyte gene expressionmyeloid cellscuba divingtranscriptome

Identifiers

PMID34177613
PMCPMC8222921
OpenAlexW3168819674

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.