Evidence map›Paper›PMID 34178337›Full record

ArticleSAGE open medicine2021

Resistant hypertension: Prevalence and profile of patients followed in a university ambulatory.

Ana Flávia Moura, José A Moura-Neto, Cibele Isaac Saad Rodrigues, Mariana O Miranda, Tulio Coelho Carvalho, Nathalia Pereira Paschoalin Carvalho, Edison Souza, José A Moura-Jr, Constança Margarida S Cruz

Open access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ana Flávia MouraEscola Bahiana de Medicina e Saúde Pública, Salvador, Bahia, Brazil.ORCID https://orcid.org/0000-0001-7368-4704
José A Moura-NetoEscola Bahiana de Medicina e Saúde Pública, Salvador, Bahia, Brazil.
Cibele Isaac Saad RodriguesFaculdade de Ciências Médicas e da Saúde. Departamento de Clínica. Pontifícia Universidade Católica de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9490-7997
Mariana O MirandaHospital Universitário Professor Edgard Santos, UFBA, Salvador, Bahia, Brazil.
Tulio Coelho CarvalhoClínica Senhor do Bonfim, Feira de Santana, Bahia, Brazil.
Nathalia Pereira Paschoalin CarvalhoClínica de Nefrologia de Serrinha, Serrinha, Bahia, Brazil.
Edison SouzaHospital Universitário Pedro Ernesto, UERJ, Rio de Janeiro, Brazil, Brazil.
José A Moura-JrClínica de Nefrologia de Serrinha, Serrinha, Bahia, Brazil.
Constança Margarida S CruzEscola Bahiana de Medicina e Saúde Pública, Salvador, Bahia, Brazil.
Escola Bahiana de Medicina e Saúde Pública · BRComplexo Hospitalar Universitário Professor Edgard Santos · BRHospital Universitário Pedro Ernesto · BRPontifícia Universidade Católica de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension affects about 36 million Brazilians. It is estimated that 10%-20% of these have resistant hypertension. These patients are at an increased risk of early target organ damage, as well as cardiovascular and renal events.

objectiveTo estimate the prevalence of resistant hypertension in a specialized outpatient clinic, to describe the sociodemographic and clinical characteristics of these patients, and to identify possible factors associated with resistant hypertension.

methodsData collection from medical records of hypertensive patients treated using oral antihypertensive drugs in optimized doses at a specialized university clinic from March 2014 to December 2014, after ethical approval statement. All patients were using appropriate antihypertensive drugs in optimized doses and assisted at a teaching-assistance clinic of internal medicine of the Bahiana School of Medicine and Public Health in Brazil.

resultsA total of 104 patients were enrolled and 31.7% (n = 33) had criteria for resistant hypertension. Of the total participants, 75.7% were female and 54.8% were black or brown. The average age was 61.7 years (SD ± 10.1). In the resistant hypertension group, 63.6% had diabetes, compared to 32.4% in the hypertension group. Among resistant hypertensive patients, 51.5% had dyslipidemia. Regarding drug treatment, 75.8% of the resistant hypertension group and 51.4% of the hypertension group used statins. Among patients with resistant hypertension, 90.9% used angiotensin II receptor blockers and 66.7%, dihydropyridine calcium channel blockers. In the resistant hypertension group, 75.8% used beta-blockers, against 25.4% in the hypertension group.

conclusionThe prevalence of hypertension was higher than that described in the global literature, which may be associated with the high percentage of black and brown ("pardos") patients in the population studied, and also because the study was performed in a specialized outpatient clinic.

Indexed as

antihypertensive agents/therapeutical usedrug resistanceHypertensionprevalence

Identifiers

PMID34178337
PMCPMC8202308
OpenAlexW3169507476

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.