Evidence map›Paper›PMID 34178728›Full record

ReviewFrontiers in cellular and infection microbiology2021

Sirtuin Control of Mitochondrial Dysfunction, Oxidative Stress, and Inflammation in Chagas Disease Models.

Xianxiu Wan, Nisha Jain Garg

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. An Update on Vaccines AgainstPathogens (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. NADCell communication and signaling : CCS · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Exploring Synergistic Inhibition of Inflammatory and Antioxidant Potential: IntegratedAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  17. Article
  18. Article
  19. SIRT1 and thrombosis.Frontiers in molecular biosciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xianxiu WanDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Nisha Jain GargDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · US

Funding

Oxidative Response Networks in Chagasic CardiomyopathyR01AI136031 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Nisha Jain Garg · 2017 to 2026
$3.6M
Pathogenesis of Oxidative Stress in Chagasic MyocarditisR01AI054578 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI GARG, NISHA JAIN · 2005 to 2016
$3.3M
Oxidative Response Networks in Chagasic CardiomyopathyR01HL094802 · NHLBI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GARG, NISHA JAIN · 2009 to 2013
$1.5M
NHLBI NIH HHS R01 HL094802NIAID NIH HHS R01 AI054578NIAID NIH HHS R01 AI136031
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chagas DiseaseSirtuinsAnimalsInflammationMitochondriaOxidative StressReactive Oxygen SpeciesReactive Oxygen SpeciesSirtuinsChagas diseasemitochondrial dysfunctionperoxisome proliferator-activated receptor gamma coactivator 1reactive oxygen speciessirtuin

Identifiers

PMID34178728
PMCPMC8221535
OpenAlexW3171478912

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.