Evidence map›Paper›PMID 34196322›Full record

ArticleInternational ophthalmology clinics2021

Ocular Inflammation and Treatment Emergent Adverse Events in Retinal Gene Therapy.

Neesurg Mehta, Deborah A Robbins, Glenn Yiu

Abstract read
In one paragraph

Article in International ophthalmology clinics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Ocular toxicity, distribution, and shedding of intravitreal AAV-eqIL-10 in horses.Molecular therapy. Methods & clinical development · 2024
    Article
  11. Review
  12. Role of FoxP3Human gene therapy · 2024
    Review
  13. Review
  14. Immunology of Retinitis Pigmentosa and Gene Therapy-Associated Uveitis.Cold Spring Harbor perspectives in medicine · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neesurg Mehta
Deborah A Robbins
Glenn Yiu

Funding

Soft drusen in rhesus macaques as a nonhuman primate model of early age-related macular degenerationR01EY032238 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI YIU, GLENN · 2021 to 2025
$3.2M
A nanoparticle platform for targeted delivery of therapeutic agents to retinal pigment epithelial or choroidal endothelial cellsK08EY026101 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI YIU, GLENN · 2016 to 2020
$1.0M
Optogenetic Control of Oxidative Stress as a Model of Geographic AtrophyR21EY031108 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI YIU, GLENN · 2019 to 2019
$312k
NEI NIH HHS K08 EY026101NEI NIH HHS R01 EY032238NEI NIH HHS R21 EY031108
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

InflammationVision DisordersGenetic TherapyHumansRetina

Identifiers

PMID34196322
PMCPMC8259781

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.