Evidence map›Paper›PMID 34197739›Full record

ArticleThe American journal of the medical sciences2021

Hyperlipidemia Influences the Accuracy of Glucometer-Measured Blood Glucose Concentrations in Genetically Diverse Mice.

Lisa J Shi, Xiwei Tang, Jiang He, Weibin Shi

Open access · greenAbstract read
In one paragraph

Article in The American journal of the medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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  5. Biomedicines · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lisa J ShiDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
Xiwei TangDepartment of Statistics, University of Virginia, Charlottesville, VA, USA.
Jiang HeDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
Weibin ShiDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA; Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, VA, USA. Electronic address: ws4v@virginia.edu.
University of Virginia · US

Funding

Genetic connections between type 2 diabetes and atherosclerosisR01DK116768 · NIDDK · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2019 to 2022
$1.6M
Genetic link between type 2 diabetes and atherosclerosisR01DK097120 · NIDDK · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2013 to 2016
$1.4M
H2 haplotype and atherosclerosisR21HL112281 · NHLBI · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2012 to 2013
$414k
NHLBI NIH HHS R21 HL112281NIDDK NIH HHS R01 DK097120NIDDK NIH HHS R01 DK116768
6 · The paper itself

Abstract

backgroundGlucometers are widely used in animal research due to simplicity and ease of utilization, but their accuracy in blood glucose assessment for hyperlipidemic mice is unknown.

methodsHere, we compared blood glucose levels measured by a glucometer with plasma glucose levels measured by a standard enzymatic assay for 325 genetically diverse F2 mice derived from LP and BALB/c (BALB) Apoe

resultsOn chow diet, lab-measured plasma glucose levels were 279.5 ± 42.6 mg/dl (mean ± SD), while blood glucose values measured by glucometer were 138.7 ± 16.6 mg/dl. The two measures had no correlation (R

conclusionsOur results indicate that hyperlipidemia affects the accuracy of glucometers in measuring blood glucose levels of mice.

Indexed as

AnimalsBlood Chemical AnalysisBlood GlucoseFemaleGenetic VariationHyperlipidemiasMaleMiceMice, Inbred BALB CMice, KnockoutBlood GlucoseBlood GlucoseDiabetesGlucometerHyperlipidemiaMice

Identifiers

PMID34197739
PMCPMC8478864
OpenAlexW3174776786

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.