Evidence map›Paper›PMID 34198907›Full record

ReviewInternational journal of molecular sciences2021

microRNAs in the Regulation of Melanogenesis.

Yekatsiaryna Hushcha, Irene Blo, Lucia Oton-Gonzalez, Giulia Di Mauro, Fernanda Martini, Mauro Tognon, Monica De Mattei

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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  19. Biocompatible exosomes derived fromRegenerative biomaterials · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yekatsiaryna HushchaMorgan S.r.l, R&D, 36050 Monteviale, VI, Italy.
Irene BloDepartment of Medical Sciences, Section of Experimental Medicine, School of Medicine, University of Ferrara, 64b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Lucia Oton-GonzalezDepartment of Medical Sciences, Section of Experimental Medicine, School of Medicine, University of Ferrara, 64b, Fossato di Mortara Street, 44121 Ferrara, Italy.ORCID 0000-0002-8515-6754
Giulia Di MauroDepartment of Medical Sciences, Section of Experimental Medicine, School of Medicine, University of Ferrara, 64b, Fossato di Mortara Street, 44121 Ferrara, Italy.ORCID 0000-0001-6739-6423
Fernanda MartiniDepartment of Medical Sciences, Section of Experimental Medicine, School of Medicine, University of Ferrara, 64b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Mauro TognonDepartment of Medical Sciences, Section of Experimental Medicine, School of Medicine, University of Ferrara, 64b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Monica De MatteiDepartment of Medical Sciences, Section of Experimental Medicine, School of Medicine, University of Ferrara, 64b, Fossato di Mortara Street, 44121 Ferrara, Italy.ORCID 0000-0002-5789-0601
University of Ferrara · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN2007Università degli Studi di Ferrara FAR AND FIR PROJECTS
6 · The paper itself

Abstract

Melanogenesis is the process leading to the synthesis of melanin, the main substance that influences skin color and plays a pivotal role against UV damage. Altered melanogenesis is observed in several pigmentation disorders. Melanogenesis occurs in specialized cells called melanocytes, physically and functionally related by means of autocrine and paracrine interplay to other skin cell types. Several external and internal factors control melanin biosynthesis and operate through different intracellular signaling pathways, which finally leads to the regulation of microphthalmia-associated transcription factor (

Indexed as

AnimalsEpigenesis, GeneticGene Expression RegulationHumansMelaninsMelanocytesMicrophthalmia-Associated Transcription FactorMicroRNAsPigmentation DisordersSkin PigmentationMelaninsMicrophthalmia-Associated Transcription FactorMicroRNAsMITF protein, humanmelanocytemelanogenesismicroRNAskin pigmentation

Identifiers

PMID34198907
PMCPMC8201055
OpenAlexW3166099141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.