Evidence map›Paper›PMID 34199566›Full record

Trial reportInternational journal of environmental research and public health2021

A Multi-Domain Group-Based Intervention to Promote Physical Activity, Healthy Nutrition, and Psychological Wellbeing in Older People with Losses in Intrinsic Capacity: AMICOPE Development Study.

Sergi Blancafort Alias, César Cuevas-Lara, Nicolás Martínez-Velilla, Fabricio Zambom-Ferraresi, Maria Eugenia Soto, Neda Tavassoli, Céline Mathieu, Eva Heras Muxella, Pablo Garibaldi, Maria Anglada and 5 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06882434 (Holistic Integration for Healthy Longevity and Aging in Place - Establishing Full-spectrum Community-based Care System for Older People to Maintain Wellbeing Pursuing Abilities), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06882434 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Holistic Integration for Healthy Longevity and Aging in Place - Establishing Full-spectrum Community-based Care System for Older People to Maintain Wellbeing Pursuing Abilities

TypeinterventionalSponsorNational Taiwan University HospitalRan2025 to 2028Enrolled600ConditionsCognitive Decline, Sarcopenia, Depression Disorders, Nutrition DisorderArmsLocal intervention program, Referral Process, Telehealth Education & Digital Integration
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Interventions that prolong multidimensional healthspan in humans: a systematic review of randomized controlled trials.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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  5. Relative impact of multidomain lifestyle interventions on deficit accumulation frailty over 24 months in the U.S. POINTER trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Trial
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  7. Associations Between Deficit Accumulation Frailty and Baseline Markers of Lifestyle in the U.S. POINTER Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Sergi Blancafort AliasFundació Salut i Envelliment (Foundation on Health and Ageing)-UAB, Universitat Autònoma de Barcelona, 08041 Barcelona, Spain.ORCID 0000-0002-5508-4702
César Cuevas-LaraNavarrabiomed, Geriatrics Department, Hospital Complex of Navarra (CHN)-Public University of Navarra (UPNA), Navarra Health Research Institute (IdisNa), 31008 Pamplona, Spain.ORCID 0000-0002-4282-8450
Nicolás Martínez-VelillaNavarrabiomed, Geriatrics Department, Hospital Complex of Navarra (CHN)-Public University of Navarra (UPNA), Navarra Health Research Institute (IdisNa), 31008 Pamplona, Spain.ORCID 0000-0001-9576-9960
Fabricio Zambom-FerraresiNavarrabiomed, Geriatrics Department, Hospital Complex of Navarra (CHN)-Public University of Navarra (UPNA), Navarra Health Research Institute (IdisNa), 31008 Pamplona, Spain.ORCID 0000-0002-8377-9827
Maria Eugenia SotoEquipe Régional Vieillissement et Prévention de la Dépendance, Gérontopôle, Centre Hospitalier Universitaire de Toulouse, 31300 Toulouse, France.
Neda TavassoliEquipe Régional Vieillissement et Prévention de la Dépendance, Gérontopôle, Centre Hospitalier Universitaire de Toulouse, 31300 Toulouse, France.ORCID 0000-0002-1591-074X
Céline MathieuEquipe Régional Vieillissement et Prévention de la Dépendance, Gérontopôle, Centre Hospitalier Universitaire de Toulouse, 31300 Toulouse, France.
Eva Heras MuxellaAgeing and Health Department in the Andorran Healthcare System, Servei Andorrà d'Atenció Sanitaria, AD700 Escaldes-Engordany, Andorra.ORCID 0000-0001-5032-3973
Pablo GaribaldiAgeing and Health Department in the Andorran Healthcare System, Servei Andorrà d'Atenció Sanitaria, AD700 Escaldes-Engordany, Andorra.
Maria AngladaAgeing and Health Department in the Andorran Healthcare System, Servei Andorrà d'Atenció Sanitaria, AD700 Escaldes-Engordany, Andorra.
Jordi AmblàsChronic Care Program, Department of Health, Generalitat de Catalunya, 08028 Barcelona, Spain.
Sebastià SantaeugèniaChronic Care Program, Department of Health, Generalitat de Catalunya, 08028 Barcelona, Spain.ORCID 0000-0002-2725-4065
Joan Carles ContelChronic Care Program, Department of Health, Generalitat de Catalunya, 08028 Barcelona, Spain.
Àlex DomingoFundació Salut i Envelliment (Foundation on Health and Ageing)-UAB, Universitat Autònoma de Barcelona, 08041 Barcelona, Spain.ORCID 0000-0003-1246-0090
Antoni Salvà CasanovasFundació Salut i Envelliment (Foundation on Health and Ageing)-UAB, Universitat Autònoma de Barcelona, 08041 Barcelona, Spain.ORCID 0000-0001-6328-3261
Centre Hospitalier Universitaire de Toulouse · FRNavarre Institute of Health Research · ESUniversitat Autònoma de Barcelona · ESUniversitat de Vic - Universitat Central de Catalunya · ESUniversity of Andorra · AD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization has developed the Integrated Care of Older People (ICOPE) strategy, a program based on the measurement of intrinsic capacity (IC) as "the composite of all physical and mental attributes on which an individual can draw". Multicomponent interventions appear to be the most effective approach to enhance IC and to prevent frailty and disability since adapted physical activity is the preventive intervention that has shown the most evidence in the treatment of frailty and risk of falls. Our paper describes the development of a multi-domain group-based intervention addressed to older people living in the community, aimed at improving and/or maintaining intrinsic capacity by means of promoting physical activity, healthy nutrition, and psychological wellbeing in older people. The process of intervention development is described following the Guidance for reporting intervention development studies in health research (GUIDED). The result of this study is the AMICOPE intervention (Aptitude Multi-domain group-based intervention to improve and/or maintain IC in Older PEople) built upon the ICOPE framework and described following the Template for Intervention Description and Replication (TIDieR) guidelines. The intervention consists of 12 face-to-face sessions held weekly for 2.5 h over three months and facilitated by a pair of health and social care professionals. This study represents the first stage of the UK Medical Research Council framework for developing and evaluating a complex intervention. The next step should be carrying out a feasibility study for the AMICOPE intervention and, at a later stage, assessing the effectiveness in a randomized controlled trial.

Indexed as

Diet, HealthyFrailtyAccidental FallsAgedExerciseHumansWorld Health Organizationageingexercisefrailtyguidelineslifestylemental healthmethodsnutritionpsychosocial intervention

Identifiers

PMID34199566
PMCPMC8199683
OpenAlexW3171319523

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.