Evidence map›Paper›PMID 34200327›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Green Tea Polyphenol Catechins Inhibit Coronavirus Replication and Potentiate the Adaptive Immunity and Autophagy-Dependent Protective Mechanism to Improve Acute Lung Injury in Mice.

Chih-Ching Yang, Chang-Jer Wu, Chen-Yen Chien, Chiang-Ting Chien

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  8. Green Tea Catechins and Skin Health.Antioxidants (Basel, Switzerland) · 2024
    Review
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  16. Pharmaceutical biology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chih-Ching YangDepartment of Life Science, School of Life Science, College of Science, National Taiwan Normal University, Taipei 11677, Taiwan.
Chang-Jer WuDepartment of Food Science, Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung 202301, Taiwan.ORCID 0000-0002-5079-5839
Chen-Yen ChienMackay Junior College of Medicine, Nursing and Management, New Taipei City 11260, Taiwan.
Chiang-Ting ChienDepartment of Life Science, School of Life Science, College of Science, National Taiwan Normal University, Taipei 11677, Taiwan.ORCID 0000-0001-7580-7069
National Taiwan Normal University · TWAsia University · TW

Funding

Ministry of Science and Technology, Taiwan NSC 92-2751-B-002-025-Y
6 · The paper itself

Abstract

Effective antiviral therapeutics are urgently required to fight severe acute respiratory syndrome (SARS) caused by a SARS coronavirus (SARS-CoV). Because polyphenol catechins could confer antioxidative, anti-inflammatory, antiviral, and antimicrobial activities, we assessed the therapeutic effects of catechins against SARS-CoV replication in Vero E6 cells, the preventive effect of catechins on CD25/CD69/CD94/CD8

Indexed as

acute lung injuryadaptive immunityautophagycatechinscytokine stormSARS-CoV replication

Identifiers

PMID34200327
PMCPMC8230342
OpenAlexW3168018304

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.