Evidence map›Paper›PMID 34201152›Full record

ReviewInternational journal of molecular sciences2021

Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry.

Tapan Behl, Ishnoor Kaur, Aayush Sehgal, Sukhbir Singh, Saurabh Bhatia, Ahmed Al-Harrasi, Gokhan Zengin, Elena Emilia Babes, Ciprian Brisc, Manuela Stoicescu and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 74 citations in OpenAlex.

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  14. PromisingFrontiers in immunology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 4 countries.

Tapan BehlDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Ishnoor KaurDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Aayush SehgalDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Sukhbir SinghDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Saurabh BhatiaAmity Institute of Pharmacy, Amity University, Gurugram 122413, India.
Ahmed Al-HarrasiNatural & Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, Nizwa 616, Oman.ORCID 0000-0002-0815-5942
Gokhan ZenginDepartment of Biology, Faculty of Science, Selcuk University Campus, 42130 Konya, Turkey.
Elena Emilia BabesDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.ORCID 0000-0001-7514-172X
Ciprian BriscDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.ORCID 0000-0003-4416-2848
Manuela StoicescuDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Mirela Marioara TomaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.
Cristian SavaDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Simona Gabriela BungauDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.ORCID 0000-0003-3236-1292
University of Oradea · ROChitkara University · INUniversity of Nizwa · OMSelçuk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With advanced technology and its development, bioinformatics is one of the avant-garde fields that has managed to make amazing progress in the pharmaceutical-medical field by modeling the infrastructural dimensions of healthcare and integrating computing tools in drug innovation, facilitating prevention, detection/more accurate diagnosis, and treatment of disorders, while saving time and money. By association, bioinformatics and pharmacovigilance promoted both sample analyzes and interpretation of drug side effects, also focusing on drug discovery and development (DDD), in which systems biology, a personalized approach, and drug repositioning were considered together with translational medicine. The role of bioinformatics has been highlighted in DDD, proteomics, genetics, modeling, miRNA discovery and assessment, and clinical genome sequencing. The authors have collated significant data from the most known online databases and publishers, also narrowing the diversified applications, in order to target four major areas (tetrad): DDD, anti-microbial research, genomic sequencing, and miRNA research and its significance in the management of current pandemic context. Our analysis aims to provide optimal data in the field by stratification of the information related to the published data in key sectors and to capture the attention of researchers interested in bioinformatics, a field that has succeeded in advancing the healthcare paradigm by introducing developing techniques and multiple database platforms, addressed in the manuscript.

Indexed as

Computational BiologyDrug DevelopmentDrug DiscoveryMicroRNAsWhole Genome SequencingAnimalsCOVID-19Drug IndustryGenome-Wide Association StudyHumansMicrobiological TechniquesPharmacovigilancePublic HealthTranslational Research, BiomedicalMicroRNAsbioinformaticsCOVID-19microbiologymicroRNApharmacovigilancepublic health

Identifiers

PMID34201152
PMCPMC8227524
OpenAlexW3168669421

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.