Evidence map›Paper›PMID 34201352›Full record

ArticleInternational journal of molecular sciences2021

Genetic Dissection of Vps13 Regulation in Yeast Using Disease Mutations from Human Orthologs.

Jae-Sook Park, Nancy M Hollingsworth, Aaron M Neiman

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Mechanistic dissection of BLTP2 targeting to ER-PM contact sites.bioRxiv : the preprint server for biology · 2026
    Article
  2. Yeast as a Model for Human Disease.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Yeast Models and Molecular Mechanisms of Neurodegenerative Diseases 2.0.International journal of molecular sciences · 2022
    Article
  6. Article
  7. Yeast as a Model to Find New Drugs and Drug Targets forInternational journal of molecular sciences · 2022
    Review
  8. Vps13 is required for efficient autophagy inContact (Thousand Oaks (Ventura County, Calif.))
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jae-Sook ParkDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.
Nancy M HollingsworthDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.ORCID 0000-0003-3300-6444
Aaron M NeimanDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.ORCID 0000-0002-6600-6996
Stony Brook University · US

Funding

ANALYSIS OF MEIOTIC CHROMOSOME SYNAPSIS IN YEASTR01GM050717 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI HOLLINGSWORTH, NANCY M. · 1995 to 2020
$8.0M
Equipment supplement for grant R01 GM072540 Assembly and Function of the Yeast Spore Wall.R01GM072540 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI NEIMAN, AARON M · 2005 to 2025
$7.1M
NIGMS NIH HHS R01 GM050717NIGMS NIH HHS R01 GM072540NIH HHS GM050717NIH HHS GM072540
6 · The paper itself

Abstract

The VPS13 family of proteins have emerged as key players in intracellular lipid transport and human health. Humans have four different

Indexed as

MutationBiological TransportCell MembraneEndoplasmic ReticulumHumansMitochondriaSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVacuolesVesicular Transport ProteinsSaccharomyces cerevisiae ProteinsVesicular Transport ProteinsVPS13 protein, S cerevisiaechorea-acanthocytosisER-phagyprotein traffickingVps13 adaptor

Identifiers

PMID34201352
PMCPMC8229349
OpenAlexW3172116290

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.