Evidence map›Paper›PMID 34201708›Full record

ArticleMolecules (Basel, Switzerland)2021

Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes.

Wiem Haj Ahmed, Nathalie Boulet, Anaïs Briot, Barry J Ryan, Gemma K Kinsella, Jeffrey O'Sullivan, Francisco Les, Josep Mercader-Barceló, Gary T M Henehan, Christian Carpéné

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Wiem Haj AhmedInstitut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0002-3330-4583
Nathalie BouletInstitut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.
Anaïs BriotInstitut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.
Barry J RyanSchool Food Science & Environmental Health, Technological University of Dublin, DOIWD85, D07 ADY7 Dublin, Ireland.ORCID 0000-0001-7213-3273
Gemma K KinsellaSchool Food Science & Environmental Health, Technological University of Dublin, DOIWD85, D07 ADY7 Dublin, Ireland.ORCID 0000-0002-6329-5841
Jeffrey O'SullivanSchool of Dental Science, Trinity College, D02 PN40 Dublin 2, Ireland.
Francisco LesDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego, 50830 Zaragoza, Spain.ORCID 0000-0002-7972-7119
Josep Mercader-BarcelóMolecular Biology and One Health (MOLONE) Research Group, Department of Fundamental Biology and Health Sciences, MOLONE, University of the Balearic Islands, 07120 Palma, Spain.ORCID 0000-0002-5293-2809
Gary T M HenehanSchool Food Science & Environmental Health, Technological University of Dublin, DOIWD85, D07 ADY7 Dublin, Ireland.ORCID 0000-0001-9208-6937
Christian CarpénéInstitut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0001-7765-6647
Trinity College Dublin · IEUniversité Toulouse III - Paul Sabatier · FRHealth Research Institute of the Balearic Islands · ESUniversidad San Jorge · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caffeine is a plant alkaloid present in food and beverages consumed worldwide. It has high lipid solubility with recognized actions in the central nervous system and in peripheral tissues, notably the adipose depots. However, the literature is scant regarding caffeine's influence on adipocyte functions other than lipolysis, such as glucose incorporation into lipids (lipogenesis) and amine oxidation. The objective of this study was to explore the direct effects of caffeine and of isobutylmethylxanthine (IBMX) on these adipocyte functions. Glucose transport into fat cells freshly isolated from mice, rats, or humans was monitored by determining [

Indexed as

AdipocytesAdipose TissueAnimalsBenzylaminesBiogenic AminesBiological TransportCaffeineDeoxyglucoseGlucoseHumansInsulinLipogenesisLipolysisMiceMonoamine OxidaseRatsbenzylamineBenzylaminesBiogenic AminesCaffeineDeoxyglucoseGlucoseInsulinmethylxanthineMonoamine OxidaseXanthinesadipocyteamine oxidasescaffeineglucose transportlipogenesislipolysismethylxanthines

Identifiers

PMID34201708
PMCPMC8270301
OpenAlexW3173743588

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.