ArticleJournal of clinical medicine2021
Health-Related Quality of Life, Depressive Symptoms, Anxiety, and Somatization Symptoms in Male and Female Patients with Chronic Tinnitus.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of Telerehabilitation Interventions for Self-Management of Tinnitus: Update of a Systematic Review.Journal of medical Internet research · 2026Pooled it
- Measurement Properties of the Patient Health Questionnaire-15 and Somatic Symptom Scale-8: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Effectiveness of Telerehabilitation Interventions for Self-management of Tinnitus: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Tinnitus, hyperacusis and somatic complaints in a diverse Norwegian clinical population: implications for assessment and rehabilitation.Annals of medicine · 2026Article
- Tinnitus Phenotypes and Their Response to the Enriched Acoustic Environment (EAE) Treatment.Brain sciences · 2026Article
- The Relationships Among Tinnitus Intensity, Complexity, Sound Intolerance, and Psychiatric Symptoms.Journal of clinical medicine · 2026Article
- Factors Affecting Health-Related Quality of Life in Patients After a Liver Transplant: A Cross-Sectional, Single-Centre, Large-Cohort Study.Journal of clinical medicine · 2025Article
- Review
- The Tinnitus Handicap Inventory Total Score: What Really Counts? Experience on a Sample of 1156 Patients.Audiology research · 2025Article
- Using Participatory Action Research to Redirect Tinnitus Treatment and Research-An Interview Study.Journal of clinical medicine · 2024Article
- Health-Related Quality of Life in Subjective, Chronic Tinnitus Patients: A Scoping Review.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Alexithymia in Patients with Somatization Difficulties and Tinnitus-Related Distress: A Systematic Review.Journal of clinical medicine · 2023Review
- Association between depression and tinnitus in US adults: A nationally representative sample.Laryngoscope investigative otolaryngology · 2023Article
- A Heterogeneous Sample of a Spanish Tinnitus Cohort.Brain sciences · 2023Article
- Associations of Tinnitus Incidence with Use of Tumor Necrosis Factor-Alpha Inhibitors among Patients with Autoimmune Conditions.Journal of clinical medicine · 2023Article
- Tinnitus and Its Relation to Depression, Anxiety, and Stress-A Population-Based Cohort Study.Journal of clinical medicine · 2023Article
- Low Sleep Satisfaction Is Related to High Disease Burden in Tinnitus.International journal of environmental research and public health · 2022Article
- Audiometric Characteristics and Tinnitus Features in a Cohort of 170 Spanish Patients.Audiology research · 2021Article
- Age-Related Hearing Loss With Tinnitus and Physical Frailty Influence the Overall and Domain-Specific Quality of Life of Chinese Community-Dwelling Older Adults.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the joint impact of tinnitus-related distress (TRD), anxiety, depressive symptoms, and other somatization symptoms on health-related quality of life (HRQoL) in female vs. male patients with chronic tinnitus.
methodThree-hundred-and-fifty-two patients with chronic tinnitus completed audiological testing and a psychological assessment battery that comprised-among other measures-German versions of the Tinnitus Questionnaire, Hospital Anxiety and Depression Scale, Somatic Symptom Scale-8, and Health-Related Quality of Life scale. Descriptive analyses examined associations as well as within- and between-gender differences of the measured variables. Gender-specific serial indirect effects analyses aimed to explain the impact of TRD on HRQoL through psychological processes, notably anxiety, depressive symptoms, and somatization symptoms.
resultsBoth female and male patients yielded lower mental than physical HRQoL and negative associations between the measured psychological variables and HRQoL. Compared to male patients, female patients reported higher levels of tinnitus-related- and wider psychological distress, other somatization symptoms (e.g., headaches), and impairments in mental and physical HRQoL. For each gender, depressive symptoms, anxiety, and somatization symptoms fully mediated the effect of TRD on mental and physical HRQoL. A double-dissociation revealed an interaction of somatization symptoms and depression on the TRD-HRQoL association in women, and of somatization symptoms and anxiety in men.
conclusionsIn patients with chronic tinnitus, psychological constructs account for reported impairments in both mental and physical HRQoL. To improve patients' HRQoL, treatment conceptualizations should consider gender-specific psychological expressions of low mood or anxiety.
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