Evidence map›Paper›PMID 34203232›Full record

ArticleMolecules (Basel, Switzerland)2021

RETRACTED: Anticancer Activity of 2-

Hae-Jung Chae, Geum-Jin Kim, Barsha Deshar, Hyun-Jin Kim, Min-Ji Shin, Hyukbean Kwon, Ui-Joung Youn, Joo-Won Nam, Sung-Hak Kim, Hyukjae Choi and 1 more

RetractedAbstract readRetracted Publication
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. RETRACTION: Lucidumol A, Purified Directly fromEvidence-based complementary and alternative medicine : eCAM · 2026
    Article
  2. RETRACTED: Chae et al. Anticancer Activity of 2-Molecules (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Evaluation ofAntioxidants (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Hae-Jung ChaeDepartment of Bioscience, Mokpo National University, Muan-gun, Joennam 58554, Korea.
Geum-Jin KimCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbukdo 38541, Korea.
Barsha DesharDepartment of Bioscience, Mokpo National University, Muan-gun, Joennam 58554, Korea.
Hyun-Jin KimDepartment of Animal Science, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Korea.
Min-Ji ShinDepartment of Bioscience, Mokpo National University, Muan-gun, Joennam 58554, Korea.
Hyukbean KwonCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbukdo 38541, Korea.
Ui-Joung YounDivision of Life Sciences, Korean Polar Research Institute (KOPRI), Incheon 21990, Korea.
Joo-Won NamCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbukdo 38541, Korea.ORCID 0000-0001-5502-0736
Sung-Hak KimDepartment of Animal Science, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Korea.
Hyukjae ChoiCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbukdo 38541, Korea.ORCID 0000-0002-7707-4767
Sung-Suk SuhDepartment of Bioscience, Mokpo National University, Muan-gun, Joennam 58554, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is one of the life-threatening ailments causing high mortality and morbidity worldwide. Despite the innovation in medical genetics, the prognosis for metastatic colorectal cancer in patients remains unsatisfactory. Recently, lichens have attracted the attention of researchers in the search for targets to fight against cancer. Lichens are considered mines of thousands of metabolites. Researchers have reported that lichen-derived metabolites demonstrated biological effects, such as anticancer, antiviral, anti-inflammatory, antibacterial, analgesic, antipyretic, antiproliferative, and cytotoxic, on various cell lines. However, the exploration of the biological activities of lichens' metabolites is limited. Thus, the main objective of our study was to evaluate the anticancer effect of secondary metabolites isolated from lichen (

Indexed as

Antineoplastic AgentsTriterpenesApoptosisColorectal NeoplasmsHCT116 CellsHumansUsneaalphitolic acidAntineoplastic AgentsTriterpenes2-O-caffeoyl alphitolic acidapoptosiscolorectal cancerHCT116lichenUsnea barbata

Identifiers

PMID34203232
PMCPMC8271524

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.