Evidence map›Paper›PMID 34204060›Full record

ReviewInternational journal of molecular sciences2021

Modelling and Refining Neuronal Circuits with Guidance Cues: Involvement of Semaphorins.

Greta Limoni

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Neuronal and Brain Maturation.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Semaphorin signaling restricts neuronal regeneration inFrontiers in cell and developmental biology · 2022
    Article
  10. Article
  11. Role of Semaphorins in Ischemic Stroke.Frontiers in molecular neuroscience · 2022
    Review
  12. Frontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Greta LimoniDepartment of Basic Neuroscience, University of Geneva Medical Center, Rue Michel-Servet 1, 1206 Geneva, Switzerland.ORCID 0000-0002-6808-9510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The establishment of neuronal circuits requires neurons to develop and maintain appropriate connections with cellular partners in and out the central nervous system. These phenomena include elaboration of dendritic arborization and formation of synaptic contacts, initially made in excess. Subsequently, refinement occurs, and pruning takes places both at axonal and synaptic level, defining a homeostatic balance maintained throughout the lifespan. All these events require genetic regulations which happens cell-autonomously and are strongly influenced by environmental factors. This review aims to discuss the involvement of guidance cues from the Semaphorin family.

Indexed as

CuesModels, NeurologicalAnimalsAxon GuidanceHumansNeuronal PlasticityNeuronsSemaphorinsSemaphorinsamyotrophic lateral sclerosisaxon pruningdendritogenesisneurodegenerationneuromuscular junctionperineuronal netplexinsretinasemaphorinssynaptic plasticity

Identifiers

PMID34204060
PMCPMC8201269

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.