Evidence map›Paper›PMID 34206792›Full record

ReviewCancers2021

Smart Biosensors for Cancer Diagnosis Based on Graphene Quantum Dots.

Daniela Iannazzo, Claudia Espro, Consuelo Celesti, Angelo Ferlazzo, Giovanni Neri

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. 0D/2D Graphene Quantum Dot-MXene Heterostructures: Luminescence, Sensing, and Electrochemical Applications.Luminescence : the journal of biological and chemical luminescence · 2026
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  16. Potential Biomedical Limitations of Graphene Nanomaterials.International journal of nanomedicine · 2023
    Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniela IannazzoDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.ORCID 0000-0003-2190-0035
Claudia EsproDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.ORCID 0000-0003-4081-1716
Consuelo CelestiDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.ORCID 0000-0003-1393-477X
Angelo FerlazzoDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.
Giovanni NeriDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.ORCID 0000-0001-8999-060X
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The timely diagnosis of cancer represents the best chance to increase treatment success and to reduce cancer deaths. Nanomaterials-based biosensors containing graphene quantum dots (GQDs) as a sensing platform show great promise in the early and sensitive detection of cancer biomarkers, due to their unique chemical and physical properties, large surface area and ease of functionalization with different biomolecules able to recognize relevant cancer biomarkers. In this review, we report different advanced strategies for the synthesis and functionalization of GQDs with different agents able to selectively recognize and convert into a signal specific cancer biomarkers such as antigens, enzymes, hormones, proteins, cancer related byproducts, biomolecules exposed on the surface of cancer cells and changes in pH. The developed optical, electrochemical and chemiluminescent biosensors based on GQDs have been shown to ensure the effective diagnosis of several cancer diseases as well as the possibility to evaluate the effectiveness of anticancer therapy. The wide linear range of detection and low detection limits recorded for most of the reported biosensors highlight their great potential in clinics for the diagnosis and management of cancer.

Indexed as

biosensorscancer biomarkerscancer diagnosisgraphene quantum dots

Identifiers

PMID34206792
PMCPMC8269110
OpenAlexW3173526884

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.