Evidence map›Paper›PMID 34206906›Full record

ArticleInternational journal of molecular sciences2021

Metabolomic Reprogramming of C57BL/6-Macrophages during Early Infection with

Maricruz Mamani-Huanca, Sandra Marcia Muxel, Stephanie Maia Acuña, Lucile Maria Floeter-Winter, Coral Barbas, Ángeles López-Gonzálvez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Effects of the methanolic extract ofOpen veterinary journal · 2026
    Article
  3. Molecular interaction assaysThe journal of venomous animals and toxins including tropical diseases · 2025
    Article
  4. Article
  5. Article
  6. Polyamine Metabolism inMedical sciences (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Article
  9. Frontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Maricruz Mamani-HuancaCentre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.ORCID 0000-0001-9180-0852
Sandra Marcia MuxelCentre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.ORCID 0000-0003-0118-5361
Stephanie Maia AcuñaDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Rua do Matão, Travessa 14, 101, São Paulo CEP-05508-090, SP, Brazil.ORCID 0000-0001-6074-4077
Lucile Maria Floeter-WinterDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Rua do Matão, Travessa 14, 101, São Paulo CEP-05508-090, SP, Brazil.ORCID 0000-0002-8954-8704
Coral BarbasCentre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.ORCID 0000-0003-4722-491X
Ángeles López-GonzálvezCentre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.ORCID 0000-0002-6363-7135
Universidad San Pablo CEU · ESUniversidade de São Paulo · BR

Funding

CEU-International Doctoral School (CEINDOConselho Nacional de Desenvolvimento Científico e Tecnológico 406351/2018-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/23519-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/23512-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/24693-9Innovation and Universities of Spain and FEDER funding Ref. RTI2018-095166-B-I00
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Parasite InteractionsMetabolomeAmino AcidsAnimalsArginaseCells, CulturedLeishmaniaLeishmaniasisMacrophagesMiceMice, Inbred BALB CMice, Inbred C57BLNitric OxideNitric Oxide Synthase Type IIIPolyaminesProtozoan ProteinsAmino AcidsArginaseNitric OxideNitric Oxide Synthase Type IIIPolyaminesProtozoan Proteinsarginasebone marrow-derived macrophagesmetabolitesnitric oxide synthasepolyamines pathway

Identifiers

PMID34206906
PMCPMC8267886
OpenAlexW3176122057

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.