Evidence map›Paper›PMID 34207643›Full record

ArticleBiology2021

Diversity of Rainbow Trout Blood B Cells Revealed by Single Cell RNA Sequencing.

Pedro Perdiguero, Esther Morel, Carolina Tafalla

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Single-cell RNA sequencing reveals IgMZoological research · 2026
    Article
  2. Article
  3. Single-cell atlas of grass carp (Zoological research · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Teleost IgDiScience · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Assessing Fish Immunotoxicity by Means ofFrontiers in immunology · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pedro PerdigueroFish Immunology and Pathology Group, Animal Health Research Center (CISA-INIA), Valdeolmos, 28130 Madrid, Spain.
Esther MorelFish Immunology and Pathology Group, Animal Health Research Center (CISA-INIA), Valdeolmos, 28130 Madrid, Spain.
Carolina TafallaFish Immunology and Pathology Group, Animal Health Research Center (CISA-INIA), Valdeolmos, 28130 Madrid, Spain.ORCID 0000-0002-0860-2976

Funding

FP7 Ideas: European Research Council ERC Consolidator Grant 2016 725061 TEMUBLYM
6 · The paper itself

Abstract

Single-cell sequencing technologies capable of providing us with immune information from dozens to thousands of individual cells simultaneously have revolutionized the field of immunology these past years. However, to date, most of these novel technologies have not been broadly applied to non-model organisms such as teleost fish. In this study, we used the 10× Genomics single cell RNA sequencing technology and used it to analyze for the first time in teleost fish the transcriptional pattern of single B cells from peripheral blood. The analysis of the data obtained in rainbow trout revealed ten distinct cell clusters that seem to be associated with different subsets and/or maturation/differentiation stages of circulating B cells. The potential characteristics and functions of these different B cell subpopulations are discussed on the basis of their transcriptomic profile. The results obtained provide us with valuable information to understand the biology of teleost B cells and offer us a repertoire of potential markers that could be used in the future to differentiate trout B cell subsets.

Indexed as

B cellsimmune markersimmunoglobulinslong non-coding RNAssingle cell transcriptomicsteleosttranscription factors

Identifiers

PMID34207643
PMCPMC8227096
OpenAlexW3168257780

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.