Evidence map›Paper›PMID 34209272›Full record

ReviewInternational journal of molecular sciences2021

The Role of Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development.

Ellie L Wagstaff, Andrea Heredero Berzal, Camiel J F Boon, Peter M J Quinn, Anneloor L M A Ten Asbroek, Arthur A Bergen

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  3. Article
  4. Retinal Organoids: Innovative Tools for Understanding Retinal Degeneration.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ellie L WagstaffDepartment of Human Genetics, Amsterdam UMC, University of Amsterdam (UvA), 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-5413-8820
Andrea Heredero BerzalDepartment of Ophthalmology, Amsterdam UMC, University of Amsterdam (UvA), 1105 AZ Amsterdam, The Netherlands.
Camiel J F BoonDepartment of Ophthalmology, Amsterdam UMC, University of Amsterdam (UvA), 1105 AZ Amsterdam, The Netherlands.
Peter M J QuinnJonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia Stem Cell Initiative, Departments of Ophthalmology, Pathology & Cell Biology, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Department of Ophthalmology, Columbia University Irving Medical Center-New York-Presbyterian Hospital, New York, NY 10032, USA.ORCID 0000-0001-9940-4264
Anneloor L M A Ten AsbroekDepartment of Human Genetics, Amsterdam UMC, University of Amsterdam (UvA), 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-7190-0784
Arthur A BergenDepartment of Human Genetics, Amsterdam UMC, University of Amsterdam (UvA), 1105 AZ Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLLeiden University Medical Center · NLNetherlands Institute for Neuroscience · NLNewYork–Presbyterian Hospital · US

Funding

H2020 Marie Skłodowska-Curie Actions 675033Stichting Steunfonds Uitzicht 2020-19
6 · The paper itself

Abstract

Early

Indexed as

Cell DifferentiationHumansOrganoidsRetinacell signalingdisease modelinghuman developmentretinal organoidsretinogenesisstem cells

Identifiers

PMID34209272
PMCPMC8268497
OpenAlexW3176150559

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.