Evidence map›Paper›PMID 34209273›Full record

Trial reportNutrients2021

Moderate Consumption of Beer (with and without Ethanol) and Menopausal Symptoms: Results from a Parallel Clinical Trial in Postmenopausal Women.

Marta Trius-Soler, María Marhuenda-Muñoz, Emily P Laveriano-Santos, Miriam Martínez-Huélamo, Gemma Sasot, Carolina E Storniolo, Ramon Estruch, Rosa M Lamuela-Raventós, Anna Tresserra-Rimbau

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marta Trius-SolerDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-2868-7142
María Marhuenda-MuñozDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-0580-4262
Emily P Laveriano-SantosDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-4852-6074
Miriam Martínez-HuélamoDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.
Gemma SasotDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.
Carolina E StornioloDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.
Ramon EstruchCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0003-1260-4445
Rosa M Lamuela-RaventósDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-1287-4560
Anna Tresserra-RimbauDepartment of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-7022-9041
Instituto de Salud Carlos III · ESUniversitat de Barcelona · ES

Funding

Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición AEI/FEDER, UEConsejo Interinstitucional de Ciencia y Tecnología AGL2016- 75329-REuropean Foundation of Alcohol Research EA 1514 EA 1515 EA 1517Generalitat de Catalunya 2017SGR 196Ministerio de Ciencia, Innovación y Universidades FPU17/00513Universitat de Barcelona APIF 2018-2019
6 · The paper itself

Abstract

The menopausal transition can be a challenging period for women's health and a trigger of uncomfortable symptoms. Beer is the main food source of isoxanthohumol, a precursor of 8-prenylnaringenin, the strongest phytoestrogen identified to date. As phytoestrogens are reported to reduce perimenopausal symptoms, we evaluated if a daily moderate consumption of beer with (AB) and without alcohol (NAB) could improve menopausal symptoms and modify cardiovascular risk factors. A total of 37 postmenopausal women were enrolled in a parallel controlled intervention trial and assigned to three study groups: 16 were administered AB (330 mL/day), 7 NAB (660 mL/day), and 14 were in the control group. After a 6-month follow-up of the 34 participants who finished the trial, both interventions (AB and NAB) significantly reduced the severity of the menopause-related symptoms (

Indexed as

BeerDrinking BehaviorAgedAnthropometryCardiometabolic Risk FactorsChromatography, LiquidClimactericEatingEthanolExerciseFemaleFlavanonesFollow-Up StudiesHumansLiverMiddle Aged8-prenylnaringeninEthanolFlavanonesPhytoestrogensalcoholcardiovascular risk factorshealthmenopausephytoestrogenspolyphenolsprenylflavonoids

Identifiers

PMID34209273
PMCPMC8308431
OpenAlexW3175331136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.