Evidence map›Paper›PMID 34209468›Full record

ReviewInternational journal of molecular sciences2021

Nanomaterials in Skin Regeneration and Rejuvenation.

Emanuela Bellu, Serenella Medici, Donatella Coradduzza, Sara Cruciani, Evzen Amler, Margherita Maioli

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Use of Hydrogels in Regenerative Medicine: Focus on Mechanical Properties.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. An Overview of Recent Developments in the Management of Burn Injuries.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Review
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emanuela BelluDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro 43/B, 07100 Sassari, Italy.
Serenella MediciDepartment of Chemistry and Pharmacy, University of Sassari, Vienna 2, 07100 Sassari, Italy.ORCID 0000-0002-4304-0251
Donatella CoradduzzaDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro 43/B, 07100 Sassari, Italy.
Sara CrucianiDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro 43/B, 07100 Sassari, Italy.ORCID 0000-0001-8632-2577
Evzen AmlerUCEEB, Czech Technical University, Trinecka 1024, 27343 Bustehrad, Czech Republic.
Margherita MaioliDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro 43/B, 07100 Sassari, Italy.ORCID 0000-0003-0187-4968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin is the external part of the human body; thus, it is exposed to outer stimuli leading to injuries and damage, due to being the tissue mostly affected by wounds and aging that compromise its protective function. The recent extension of the average lifespan raises the interest in products capable of counteracting skin related health conditions. However, the skin barrier is not easy to permeate and could be influenced by different factors. In the last decades an innovative pharmacotherapeutic approach has been possible thanks to the advent of nanomedicine. Nanodevices can represent an appropriate formulation to enhance the passive penetration, modulate drug solubility and increase the thermodynamic activity of drugs. Here, we summarize the recent nanotechnological approaches to maintain and replace skin homeostasis, with particular attention to nanomaterials applications on wound healing, regeneration and rejuvenation of skin tissue. The different nanomaterials as nanofibers, hydrogels, nanosuspensions, and nanoparticles are described and in particular we highlight their main chemical features that are useful in drug delivery and tissue regeneration.

Indexed as

Drug Delivery SystemsRejuvenationAnimalsHumansNanostructuresRegenerationSkinSkin Physiological Phenomenacellular mechanismsnanomaterialsregenerative medicineskinstem cells

Identifiers

PMID34209468
PMCPMC8268279

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.