Evidence map›Paper›PMID 34209507›Full record

ArticleNutrients2021

Effects of Bacterial CLPB Protein Fragments on Food Intake and PYY Secretion.

Manon Dominique, Nicolas Lucas, Romain Legrand, Illona-Marie Bouleté, Christine Bôle-Feysot, Camille Deroissart, Fatima Léon, Séverine Nobis, Jean-Claude do Rego, Grégory Lambert and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Protein Extract of a Probiotic Strain ofInternational journal of molecular sciences · 2023
    Article
  11. Microorganisms · 2022
    Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Manon DominiqueTargEDys SA, 76183 Rouen, France.
Nicolas LucasTargEDys SA, 76183 Rouen, France.
Romain LegrandTargEDys SA, 76183 Rouen, France.ORCID 0000-0003-3652-0537
Illona-Marie BouletéTargEDys SA, 76183 Rouen, France.
Christine Bôle-FeysotInserm UMR1073, Nutrition, Gut and Brain Laboratory, University of Rouen Normandy, 76183 Rouen, France.
Camille DeroissartTargEDys SA, 76183 Rouen, France.
Fatima LéonInstitute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, 76183 Rouen, France.
Séverine NobisInstitute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, 76183 Rouen, France.
Jean-Claude do RegoInstitute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, 76183 Rouen, France.
Grégory LambertTargEDys SA, 76183 Rouen, France.ORCID 0000-0002-3840-3935
Pierre DéchelotteTargEDys SA, 76183 Rouen, France.ORCID 0000-0001-5224-6166
Inserm · FRInstitute for Research and Innovation in Biomedicine · FR

Funding

European Regional Development Fund (ERDF) European Regional Development Fund (ERDF)Ministry of Industry and Technology Ministry of Industry and TechnologyTargEDys SA TargEDys SA
6 · The paper itself

Abstract

CLPB (Caseinolytic peptidase B) protein is a conformational mimetic of α-MSH, an anorectic hormone. Previous in vivo studies have already shown the potential effect of CLPB protein on food intake and on the production of peptide YY (PYY) by injection of

Indexed as

AnimalsAntibodies, BacterialAppetite DepressantsBlotting, WesternCell Culture TechniquesDNA FragmentationEatingEndopeptidase ClpEnzyme-Linked Immunosorbent AssayEscherichia coliEscherichia coli ProteinsHeat-Shock ProteinsInjections, IntraperitonealMaleMiceMice, Inbred C57BLAntibodies, BacterialAppetite DepressantsClpB protein, E coliEndopeptidase ClpEscherichia coli ProteinsHeat-Shock ProteinsPeptide YYcaseinolytic peptidase Bfood intakefragmentsin vivopeptide YY

Identifiers

PMID34209507
PMCPMC8308458
OpenAlexW3174163389

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.