Evidence map›Paper›PMID 34209804›Full record

Trial reportNutrients2021

Effects of Fermented Milk Containing

Xiaomei Zhang, Shanbin Chen, Ming Zhang, Fazheng Ren, Yimei Ren, Yixuan Li, Ning Liu, Yan Zhang, Qi Zhang, Ran Wang

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 14 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 14 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
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  3. [Seoul Consensus on Clinical Practice Guidelines for Functional Constipation].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Guideline
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  11. Probiotics for the treatment of depression and its comorbidities: A systemic review.Frontiers in cellular and infection microbiology · 2023
    Pooled it
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  15. Trial
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiaomei ZhangDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.
Shanbin ChenDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.
Ming ZhangSchool of Food and Chemical Engineering, Beijing Technology and Business University, Beijing 100048, China.ORCID 0000-0003-1175-4636
Fazheng RenDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.
Yimei RenKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Government China Agricultural University, Beijing 100083, China.
Yixuan LiDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.
Ning LiuDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.ORCID 0000-0002-7484-0534
Yan ZhangHebei Engineering Research Center of Animal Product, Sanhe 065200, China.
Qi ZhangDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.
Ran WangDepartment of Nutrition and Health, China Agricultural University, Beijing 100091, China.ORCID 0000-0001-7125-5690
China Agricultural University · CNBeijing Technology and Business University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics have been shown to benefit patients with constipation and depression, but whether they specifically alleviate constipation in patients with depression remains unclear. The aim of this study was to investigate the effect of

Indexed as

Lacticaseibacillus paracaseiAdultAnimalsConstipationCultured Milk ProductsDepressionDouble-Blind MethodFecesFemaleGastrointestinal MicrobiomeHumansMaleMiddle AgedProbioticsTreatment OutcomeconstipationdepressionLacticaseibacillus paracasei strain Shirota (LcS)

Identifiers

PMID34209804
PMCPMC8308326
OpenAlexW3173601433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.