Evidence map›Paper›PMID 34210781›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

The Serine Protease Homolog, Scarface, Is Sensitive to Nutrient Availability and Modulates the Development of the

Esteban G Contreras, Álvaro Glavic, Andrea H Brand, Jimena A Sierralta

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. The Set of Serine Peptidases of theInternational journal of molecular sciences · 2024
    Article
  9. TBI and Tau Loss of Function Both Affect Naïve Ethanol Sensitivity inInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. Drosophila glia take shape to sculpt the nervous system.Current opinion in neurobiology · 2023
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Esteban G ContrerasBiomedical Neuroscience Institute and Department of Neuroscience, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile eocontre@uc.cl jsierral@uchile.cl.
Álvaro GlavicFund for Research Centers in Prioritary Areas Center for Genome Regulation, Faculty of Science, Universidad de Chile, Santiago 7800024, Chile.
Andrea H BrandThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 1QN, England.
Jimena A SierraltaBiomedical Neuroscience Institute and Department of Neuroscience, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile eocontre@uc.cl jsierral@uchile.cl.
University of Chile · CLWellcome/Cancer Research UK Gurdon Institute · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The adaptable transcriptional response to changes in food availability not only ensures animal survival but also lets embryonic development progress. Interestingly, the CNS is preferentially protected from periods of malnutrition, a phenomenon known as "brain sparing." However, the mechanisms that mediate this response remain poorly understood. To get a better understanding of this, we used

Indexed as

AnimalsBlood-Brain BarrierDrosophila melanogasterDrosophila ProteinsFemaleMaleMalnutritionNeural Stem CellsNeurogenesisNeurogliaSerine ProteasesDrosophila Proteinsscaf protein, DrosophilaSerine Proteasesblood–brain barrierDrosophila melanogasterglial cellsnutrient restrictionScarfaceserine protease homolog

Identifiers

PMID34210781
PMCPMC8318086
OpenAlexW3173203845

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.