Evidence map›Paper›PMID 34211592›Full record

ReviewTherapeutic advances in musculoskeletal disease2021

Biomarkers for interstitial lung disease and acute-onset diffuse interstitial lung disease in rheumatoid arthritis.

Hiroshi Furukawa, Shomi Oka, Takashi Higuchi, Kota Shimada, Atsushi Hashimoto, Toshihiro Matsui, Shigeto Tohma

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in musculoskeletal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07003451 (Novel Biomarkers in Assessment of Interstitial Lung Disease Associated With Rheumatoid Arthritis Patients), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07003451 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Novel Biomarkers in Assessment of Interstitial Lung Disease Associated With Rheumatoid Arthritis Patients

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled60ConditionsRheumatoid Arthritis, Interstitial Lung DiseaseArmsCalprotectin Level
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Acute Exacerbations of Interstitial Lung Diseases: Focus on Biomarkers.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hiroshi FurukawaDepartment of Rheumatology, National Hospital Organization Tokyo National Hospital, 3-1-1 Takeoka, Kiyose 204-8585, Japan.ORCID https://orcid.org/0000-0003-1353-8056
Shomi OkaDepartment of Rheumatology, National Hospital Organization Tokyo National Hospital, Kiyose, Japan.
Takashi HiguchiDepartment of Rheumatology, National Hospital Organization Tokyo National Hospital, Kiyose, Japan.
Kota ShimadaDepartment of Rheumatology, National Hospital Organization Sagamihara National Hospital, Minami-ku, Sagamihara, Japan.
Atsushi HashimotoDepartment of Rheumatology, National Hospital Organization Sagamihara National Hospital, Minami-ku, Sagamihara, Japan.
Toshihiro MatsuiClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Minami-ku, Sagamihara, Japan.
Shigeto TohmaDepartment of Rheumatology, National Hospital Organization Tokyo National Hospital, Kiyose, Japan.
National Sagamihara Hospital · JPTokyo National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial lung disease (ILD) is frequently a complication of rheumatoid arthritis (RA) as an extra-articular manifestation which has a poor prognosis. Acute-onset diffuse ILD (AoDILD) occasionally occurs in RA and includes acute exacerbation of ILD, drug-induced ILD, and

Indexed as

acute-onset diffusebiomarkerinterstitial lung diseaserheumatoid arthritis

Identifiers

PMID34211592
PMCPMC8216360
OpenAlexW3175932364

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.