Evidence map›Paper›PMID 34212146›Full record

ArticleRSC chemical biology2021

Fluorescence lifetime predicts performance of voltage sensitive fluorophores in cardiomyocytes and neurons.

Steven C Boggess, Julia R Lazzari-Dean, Benjamin K Raliski, Dong Min Mun, Amy Y Li, Joshua L Turnbull, Evan W Miller

Open access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Fluorescence-lifetime optical electrophysiology in contracting cardiomyocytes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Water-Soluble Molecular Wires for Membrane Potential Imaging.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A red-emitting carborhodamine for monitoring and measuring membrane potential.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Flipping the Switch: Reverse-Demand Voltage-Sensitive Fluorophores.Journal of the American Chemical Society · 2022
    Article
  13. Article
  14. Article
  15. Phosphonofluoresceins: Synthesis, Spectroscopy, and Applications.Journal of the American Chemical Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Steven C BoggessDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Julia R Lazzari-DeanDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Benjamin K RaliskiDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Dong Min MunDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Amy Y LiDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Joshua L TurnbullDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Evan W MillerDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Berkeley College · US

Funding

Univ of Calif Berkeley Chemistry-Biology Interface ProgramT32GM066698 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHANG, CHRISTOPHER J., FRANCIS, MATTHEW B · 2004 to 2023
$7.5M
Proposal for Central California 900 MHZ NMR SpectrometerP41GM068933 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI WEMMER, DAVID E · 2003 to 2007
$5.9M
New Chemical Tools for Exploring Cellular PhysiologyR35GM119855 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MILLER, EVAN WALKER · 2016 to 2020
$1.3M
Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, BerkeleyS10OD024998 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARTWIG, JOHN F · 2018 to 2018
$265k
NIGMS NIH HHS P41 GM068933NIGMS NIH HHS R35 GM119855NIGMS NIH HHS T32 GM066698NIH HHS S10 OD024998
6 · The paper itself

Abstract

Voltage imaging with fluorescent indicators offers a powerful complement to traditional electrode or Ca

Identifiers

PMID34212146
PMCPMC8240514
OpenAlexW3112038715

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.