Evidence map›Paper›PMID 34212256›Full record

ReviewIntensive care medicine experimental2021

The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis.

Mark E Nunnally, Ricard Ferrer, Greg S Martin, Ignacio Martin-Loeches, Flavia R Machado, Daniel De Backer, Craig M Coopersmith, Clifford S Deutschman, Surviving Sepsis Campaign Reasearch Committee

Open access · goldAbstract readReview
In one paragraph

Review in Intensive care medicine experimental, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 52 citations in OpenAlex.

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  16. Development of a mobile application for health education about sepsis.Revista da Escola de Enfermagem da U S P · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Mark E NunnallyNew York University School of Medicine, New York, NY, USA. mark.nunnally@nyulangone.org.ORCID http://orcid.org/0000-0003-2129-4733
Ricard FerrerIntensive Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Greg S MartinDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Grady Memorial Hospital and Emory Critical Care Center, Emory University, Atlanta, GA, USA.
Ignacio Martin-LoechesMultidisciplinary Intensive Care Research Organization (MICRO), Department of Intensive Care Medicine, St. James's University Hospital, Trinity Centre for Health Sciences, Dublin, Ireland.
Flavia R MachadoUniversidade Federal de São Paulo, Sao Paulo, Brazil.
Daniel De BackerChirec Hospitals, Université Libre de Bruxelles, Brussels, Belgium.
Craig M CoopersmithDepartment of Surgery and Emory Critical Care Center, Emory University, Atlanta, GA, USA.
Clifford S DeutschmanDepartment of Pediatrics, Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY, USA.
Surviving Sepsis Campaign Reasearch Committee
Emory University · USGrady Memorial Hospital · USNew York University · USNorthwell Health · USSt. James's Hospital · IEUniversidade Federal de São Paulo · BRUniversité Libre de Bruxelles · BEVall d'Hebron Institut de Recerca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify priorities for administrative, epidemiologic and diagnostic research in sepsis.

designAs a follow-up to a previous consensus statement about sepsis research, members of the Surviving Sepsis Campaign Research Committee, representing the European Society of Intensive Care Medicine and the Society of Critical Care Medicine addressed six questions regarding care delivery, epidemiology, organ dysfunction, screening, identification of septic shock, and information that can predict outcomes in sepsis.

methodsSix questions from the Scoring/Identification and Administration sections of the original Research Priorities publication were explored in greater detail to better examine the knowledge gaps and rationales for questions that were previously identified through a consensus process.

resultsThe document provides a framework for priorities in research to address the following questions: (1) What is the optimal model of delivering sepsis care?; (2) What is the epidemiology of sepsis susceptibility and response to treatment?; (3) What information identifies organ dysfunction?; (4) How can we screen for sepsis in various settings?; (5) How do we identify septic shock?; and (6) What in-hospital clinical information is associated with important outcomes in patients with sepsis?

conclusionsThere is substantial knowledge of sepsis epidemiology and ways to identify and treat sepsis patients, but many gaps remain. Areas of uncertainty identified in this manuscript can help prioritize initiatives to improve an understanding of individual patient and demographic heterogeneity with sepsis and septic shock, biomarkers and accurate patient identification, organ dysfunction, and ways to improve sepsis care.

Indexed as

EpidemiologyOrgan dysfunctionOutcomesPrioritiesResearchScreeningSepsisSeptic shockSurviving Sepsis Campaign

Identifiers

PMID34212256
PMCPMC8249046
OpenAlexW3175993393

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.