Evidence map›Paper›PMID 34214459›Full record

ArticleThe American journal of medicine2021

Patient Characteristics and Outcomes of Type 2 Myocardial Infarction During Heart Failure Hospitalizations in the United States.

Salik Nazir, Abdul Mannan Khan Minhas, Ishan S Kamat, Robert W Ariss, George V Moukarbel, Juan Carlos Plana Gomez, Savitri Fedson, Ajith Nair, Biykem Bozkurt, Hani Jneid

Open access · greenAbstract read
In one paragraph

Article in The American journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Salik NazirSection of Cardiology, University of Toledo Medical Center, Toledo, Ohio.
Abdul Mannan Khan MinhasDivision of Medicine, Forrest General Hospital, Hattiesburg, Mississippi.
Ishan S KamatSection of Cardiology, Baylor College of Medicine, Houston, Texas.
Robert W ArissSection of Cardiology, University of Toledo Medical Center, Toledo, Ohio.
George V MoukarbelSection of Cardiology, University of Toledo Medical Center, Toledo, Ohio.
Juan Carlos Plana GomezSection of Cardiology, Baylor College of Medicine, Houston, Texas.
Savitri FedsonSection of Cardiology, Baylor College of Medicine, Houston, Texas.
Ajith NairSection of Cardiology, Baylor College of Medicine, Houston, Texas.
Biykem BozkurtSection of Cardiology, Baylor College of Medicine, Houston, Texas.
Hani JneidSection of Cardiology, Baylor College of Medicine, Houston, Texas. Electronic address: Jneid@bcm.edu.
Baylor College of Medicine · USUniversity of Toledo Medical Center · USForrest General Hospital · US

Funding

Research Training Program in Cardiovascular SurgeryT32HL139430 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Todd K Rosengart · 2018 to 2026
$2.9M
NHLBI NIH HHS T32 HL139430
6 · The paper itself

Abstract

backgroundType 2 myocardial infarction (MI) is increasingly diagnosed in patients with heart failure (HF). A paucity of data exists pertinent to the contemporary prevalence and impact of type 2 MI in patients with HF. We studied the patient profiles and the prognostic impact of type 2 MI on outcomes of HF hospitalizations.

methodsThe Nationwide Readmission Database 2018 was queried for patients with HF hospitalizations with and without type 2 MI. Baseline characteristics, inpatient outcomes, and 30-day all-cause readmissions between both cohorts were compared.

resultsOf 1,072,674 primary HF hospitalizations included in the study, 28,813 (2.7%) had type 2 MI. Patients with type 2 MI were more likely to be males (56.5% vs 51.6%; P < .001) and had a higher prevalence of hypertension (94% vs 92.2%; P < .001), prior myocardial infarction (17.1% vs 14.9%; P < .001), anemia (9.1% vs 8.1%; P < .001), chronic kidney disease (55.7% vs 49.4%; P < .001), neurological disorders (9.4% vs 7.3%; P < .001), and weight loss (7.3% vs 5.6%; P < .001). Compared with their counterparts without type 2 MI, patients with HF with type 2 MI had significantly higher in-hospital mortality (adjusted odds ratio [aOR], 1.53; 95% confidence interval [CI], 1.37-1.72), hospital costs (adjusted parameter estimate, $1785; 95% CI, 1388-2182), discharge to nursing facility (aOR, 1.22; 95% CI, 1.15-1.29), longer length of stay (adjusted parameter estimate, 0.53; 95% CI, 0.42-0.64), and rate of 30-day all-cause readmissions (aOR, 1.06; 95% CI, 1.01-1.12).

conclusionType 2 MI in patients hospitalized with HF is associated with higher mortality and resource utilization in the United States.

Indexed as

Hospital MortalityAgedAnemiaCase-Control StudiesComorbidityFemaleHeart FailureHospital CostsHospitalizationHumansHypertensionLength of StayMaleMyocardial InfarctionNervous System DiseasesNursing HomesHeart failureOutcomes researchReadmissionsType 2 myocardial infarction

Identifiers

PMID34214459
PMCPMC9131468
OpenAlexW3175109993

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.