SynthesisBJOG : an international journal of obstetrics and gynaecology2021
A core outcome set for the treatment of pregnant women with pregestational diabetes: an international consensus study.
Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Impact of Automated Insulin Delivery on Glycemic Profile and Maternal/Neonatal Outcomes in Pregnancy: A Review of the Evidence From Observational Studies.Journal of diabetes science and technology · 2026Review
- Development and Content of Core Outcome Sets in Neonatology-A Scoping Review.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Systematic identification of existing core outcomes related to preterm birth and the development of a core outcome set for preterm birth in Aotearoa New Zealand.Pediatric investigation · 2025Article
- Glycaemic control in labour with diabetes: GILD, a scoping study.Health technology assessment (Winchester, England) · 2025Article
- Heterogeneity of Gestational Diabetes and Risk for Adverse Pregnancy Outcome: A Cohort Study.The Journal of clinical endocrinology and metabolism · 2025Article
- A narrative review of metformin in pregnancy: Navigating benefit and uncertainty.Diabetes, obesity & metabolism · 2025Review
- Health-related quality of life in pregnant women with type 1 diabetes and associations with maternal and neonatal complications.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Rural-urban disparities in pregestational and gestational diabetes in pregnancy: Serial, cross-sectional analysis of over 12 million pregnancies.BJOG : an international journal of obstetrics and gynaecology · 2024Article
- The development of a core outcome set for studies of pregnant women with multimorbidity.BMC medicine · 2023Article
- Closed-loop insulin delivery in pregnant women with type 1 diabetes (CRISTAL): a multicentre randomized controlled trial - study protocol.BMC pregnancy and childbirth · 2023Article
- Diabetic Ketoacidosis in Pregnancy: Clinical Risk Factors, Presentation, and Outcomes.The Journal of clinical endocrinology and metabolism · 2022Article
- OSFCOS: A core outcome set for clinical trials on oral submucous fibrosis management.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
29 authors at 17 institutions in 11 countries.
Funding
Abstract
objectiveTo develop a core outcome set (COS) for randomised controlled trials (RCTs) evaluating the effectiveness of interventions for the treatment of pregnant women with pregestational diabetes mellitus (PGDM).
designA consensus developmental study.
settingInternational. POPULATION: Two hundred and five stakeholders completed the first round.
methodsThe study consisted of three components. (1) A systematic review of the literature to produce a list of outcomes reported in RCTs assessing the effectiveness of interventions for the treatment of pregnant women with PGDM. (2) A three-round, online eDelphi survey to prioritise these outcomes by international stakeholders (including healthcare professionals, researchers and women with PGDM). (3) A consensus meeting where stakeholders from each group decided on the final COS.
main outcome measuresAll outcomes were extracted from the literature.
resultsWe extracted 131 unique outcomes from 67 records meeting the full inclusion criteria. Of the 205 stakeholders who completed the first round, 174/205 (85%) and 165/174 (95%) completed rounds 2 and 3, respectively. Participants at the subsequent consensus meeting chose 19 outcomes for inclusion into the COS: trimester-specific haemoglobin A1c, maternal weight gain during pregnancy, severe maternal hypoglycaemia, diabetic ketoacidosis, miscarriage, pregnancy-induced hypertension, pre-eclampsia, maternal death, birthweight, large for gestational age, small for gestational age, gestational age at birth, preterm birth, mode of birth, shoulder dystocia, neonatal hypoglycaemia, congenital malformations, stillbirth and neonatal death.
conclusionsThis COS will enable better comparison between RCTs to produce robust evidence synthesis, improve trial reporting and optimise research efficiency in studies assessing treatment of pregnant women with PGDM. TWEETABLE ABSTRACT: 165 key stakeholders have developed #Treatment #CoreOutcomes in pregnant women with #diabetes existing before pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.