Evidence map›Paper›PMID 34221665›Full record

ArticleBiomedical optics express2021

Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography.

Feng Yan, Gokhan Gunay, Trisha I Valerio, Chen Wang, Jayla A Wilson, Majood S Haddad, Maegan Watson, Michael O Connell, Noah Davidson, Kar-Ming Fung and 2 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Feng YanStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.ORCID https://orcid.org/0000-0001-9926-7554
Gokhan GunayStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Trisha I ValerioStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Chen WangStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Jayla A WilsonStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Majood S HaddadStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Maegan WatsonStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Michael O ConnellStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Noah DavidsonStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Kar-Ming FungDepartment of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA.
Handan AcarStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.
Qinggong TangStephenson School of Biomedical Engineering, University of Oklahoma, OK 73019, USA.

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
TUMOR RESISTANCE MECHANISMS TO ANTI-VEGF THERAPY IN PROSTATE CANCER (Sukyung Woo)P20GM103639 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI DHANASEKARAN, DANNY N. · 2012 to 2022
$21.3M
NCI NIH HHS P30 CA225520NIGMS NIH HHS P20 GM103639
6 · The paper itself

Abstract

The three-dimensional (3D) tumor spheroid model is a critical tool for high-throughput ovarian cancer research and anticancer drug development

Identifiers

PMID34221665
PMCPMC8221959

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.