Evidence map›Paper›PMID 34224834›Full record

ArticleJournal of clinical epidemiology2021

Abstracts for reports of randomised trials of COVID-19 interventions had low quality and high spin.

Dongguang Wang, Lingmin Chen, Lian Wang, Fang Hua, Juan Li, Yuxi Li, Yonggang Zhang, Hong Fan, Weimin Li, Mike Clarke

Abstract read
In one paragraph

Article in Journal of clinical epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. The importance of meta-research in dentistry.Evidence-based dentistry · 2023
    Article
  4. Article
  5. Article
  6. Massive covidization of research citations and the citation elite.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. A Synthesis of the Formats for Correcting Erroneous and Fraudulent Academic Literature, and Associated Challenges.Journal for general philosophy of science = Zeitschrift fur allgemeine Wissenschaftstheorie · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dongguang WangDepartment of Respiratory and Critical Care Medicine, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China.
Lingmin ChenDepartment of Anesthesiology and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University & The Research Units of West China (2018RU012, Chinese Academy of Medical Sciences), Chengdu, China.
Lian WangDepartment of Respiratory and Critical Care Medicine, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China.
Fang HuaCenter for Evidenced-Based Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China; Cochrane Oral Health, Division of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Center, Manchester, UK.
Juan LiSchool of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yuxi LiSchool of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yonggang ZhangDepartment of Periodical Press, West China Hospital, Sichuan University, Chengdu, China.
Hong FanDepartment of Respiratory and Critical Care Medicine, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China. Electronic address: fanhongfan@qq.com.
Weimin LiDepartment of Respiratory and Critical Care Medicine, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China. Electronic address: weimi003@yahoo.com.
Mike ClarkeNorthern Ireland Clinical Trials Unit and Methodology Hub, Centre for Public Health, Queen's University Belfast, Belfast, UK. Electronic address: m.clarke@qub.ac.uk.

Funding

Medical Research Council G0901530
6 · The paper itself

Abstract

objectivesTo assess the reporting quality of abstracts for published randomized controlled trials (RCTs) of interventions for coronavirus disease 2019 (COVID-19), including the use of spin strategies and the level of spin for RCTs with statistically non-significant primary outcomes, and to explore potential predictors for reporting quality and the severity of spin. STUDY DESIGN AND

settingPubMed was searched to find RCTs that tested interventions for COVID-19, and the reporting quality and spin in the abstracts were assessed. Linear regression analyses were used to identify potential predictors.

resultsForty RCT abstracts were included in our assessment of reporting quality, and a higher word count in the abstract was significantly correlated with higher reporting scores (95% CI 0.044 to 0.658, P=0.026). Multiple spin strategies were identified. Our multivariate analyses showed that geographical origin was associated with severity of spin, with research from non-Asian regions containing fewer spin strategies (95% CI -0.760 to -0.099, P=0.013).

conclusionsThe reporting quality of abstracts of RCTs of interventions for COVID-19 is far from satisfactory. A relatively high proportion of the abstracts contained spin, and the findings reported in the results and conclusion sections of these abstracts need to be interpreted with caution.

Indexed as

abstract, COVID-19, randomized controlled trial, primary outcome, reporting quality, spin Abbreviations RCT: randomized controlled trialCONSORT: consolidated standards of reporting trialsCOVID-19: coronavirus disease 2019IQR: interquartile rangeSARS-CoV-2: severe acute respiratory syndrome coronavirus 2

Identifiers

PMID34224834
PMCPMC8253697

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.