Evidence map›Paper›PMID 34227410›Full record

SynthesisChronic respiratory disease

The burden of chronic respiratory diseases in adults in Nepal: A systematic review.

Winifred Ekezie, Alex Robert Jenkins, Ian Philip Hall, Catrin Evans, Rajendra Koju, Om Prakash Kurmi, Charlotte Emma Bolton

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Winifred EkezieNIHR Nottingham BRC Respiratory Theme, School of Medicine, University of Nottingham, Nottingham, UK.
Alex Robert JenkinsNIHR Nottingham BRC Respiratory Theme, School of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0002-4384-2342
Ian Philip HallNIHR Nottingham BRC Respiratory Theme, School of Medicine, University of Nottingham, Nottingham, UK.
Catrin EvansNottingham Centre for Evidence Based Healthcare, School of Health Sciences, 6123University of Nottingham, Nottingham, UK.
Rajendra KojuDepartment of Medicine, 375889Dhulikhel Hospital, Dhulikhel, Nepal.
Om Prakash KurmiDepartment of Medicine, 3710McMaster University, Hamilton, Ontario, Canada.
Charlotte Emma BoltonNIHR Nottingham BRC Respiratory Theme, School of Medicine, University of Nottingham, Nottingham, UK.
University of Nottingham · GBDhulikhel Hospital · NPMcMaster University · CA

Funding

Medical Research Council G1000861
6 · The paper itself

Abstract

While chronic lung disease causes substantial global morbidity and mortality, global estimates have primarily been based on broad assumptions. Specific country data from low-income countries such as Nepal are limited. This review assessed primary evidence on chronic respiratory disease burden among adults in Nepal. A systematic search was performed in June 2019 (updated May 2020) for studies through nine databases. High levels of heterogeneity deemed a narrative synthesis appropriate. Among 27 eligible studies identified, most were low-moderate quality with cross-sectional and retrospective study design. Chronic lung diseases identified were chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis and restrictive lung diseases. Studies were categorised as: (i) community-based, (ii) hospital-based and (iii) comorbidity-related and disease burden. Reported disease prevalence varied widely (COPD, 1.67-14.3%; asthma, 4.2-8.9%). The prevalence of airflow obstruction was higher among rural dwellers (15.8%) and those exposed to household air pollution from domestic biomass burning as opposed to liquid petroleum gas users (Odds Ratio: 2.06). Several comorbidities, including hypertension and diabetes mellitus added to the disease burden. The review shows limited literature on lung disease burden in Nepal. Publications varied in terms of overall quality. Good quality research studies with prospective cohorts related to respiratory conditions are required.

Indexed as

Pulmonary Disease, Chronic ObstructiveAdultCross-Sectional StudiesHumansNepalPrevalenceProspective StudiesRetrospective StudiesChronic respiratory diseaseglobal lung healthlung functionNepalprevalence

Identifiers

PMID34227410
PMCPMC8264743
OpenAlexW3178780830

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.