ArticleAmerican journal of physiology. Endocrinology and metabolism2021
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance.
Jaclyn A Wisinski, Austin Reuter, Darby C Peter, Michael D Schaid, Rachel J Fenske, Michelle E Kimple
Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors at 2 institutions in 1 country.
Jaclyn A WisinskiDepartment of Biology, University of Wisconsin-LaCrosse, La Crosse, Wisconsin.
Austin ReuterResearch Service, William S. Middleton Memorial VA Hospital, Madison, Wisconsin.
Darby C PeterResearch Service, William S. Middleton Memorial VA Hospital, Madison, Wisconsin.
Michael D SchaidResearch Service, William S. Middleton Memorial VA Hospital, Madison, Wisconsin.
Rachel J FenskeResearch Service, William S. Middleton Memorial VA Hospital, Madison, Wisconsin.
Michelle E KimpleResearch Service, William S. Middleton Memorial VA Hospital, Madison, Wisconsin.ORCID 0000-0003-0869-9699
University of Wisconsin–Madison · USUniversity of Wisconsin–La Crosse · US
Funding
TRAINING IN NUTRITIONT32DK007665 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI GUY E GROBLEWSKI, Chi- Liang Eric Yen · 1993 to 2026
$9.2M
Molecular Mechanisms of Dysfunctional Prostaglandin Signaling in the Beta-CellR01DK102598 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI KIMPLE, MICHELLE E · 2014 to 2018
$1.7M
Regulation of G-Protein SignalingR01DK076488 · NIDDK · DUKE UNIVERSITY · PI CASEY, PATRICK J. · 2006 to 2009
$1.1M
G(alpha)Z signaling in insulin secretion and glucose toleranceK01DK080845 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI KIMPLE, MICHELLE E · 2008 to 2010
$301k
Role of inhibitory G protein signaling in regulating beta-cell function and survival in the type 1 diabetic stateF31DK109698 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI FENSKE, RACHEL J · 2017 to 2018
$87k
G Protein Mediated Mechanisms of Beta Cell Death Dysfunction and Decompensation in DiabetesI01BX003700 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI KIMPLE, MICHELLE E · 2018 to 2021
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance. · full record | Socratic