ReviewImmunology2021
Haemocyte-mediated immunity in insects: Cells, processes and associated components in the fight against pathogens and parasites.
Review in Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 190 citations in OpenAlex.
- Article
- Is the developmental stage important for the plasticity of transgenerational immune priming?Biology open · 2026Article
- Parallel Recovery Dynamics of Circulating and Tissue-Resident Hemocytes Following Hemolymph Withdrawal inInternational journal of molecular sciences · 2026Article
- AnvRV virus in the parasitoid waspMicrobiology spectrum · 2026Article
- When Small Meets Smaller: Immune Modulation and Virulence Strategies in Insect-Bacteria Interactions.Insects · 2026Review
- Insect immunity unveiled: exploring the molecular and cellular defenses against microbial threats.Archives of microbiology · 2026Review
- Functional Analysis ofInsects · 2026Article
- Biocontrol Mechanisms of a ChineseInsects · 2026Article
- Infestation by Phorid Flies Disrupts Behavior and Immune Function in Honey Bees Monitored by Radio-frequency Identification.Neotropical entomology · 2026Article
- Review
- Recent insights in the development and functions of insect hemocytes.Current opinion in insect science · 2026Review
- IbinA and IbinB regulate the Toll pathway-mediated immune response in Drosophila melanogaster.BMC biology · 2026Article
- Article
- Time-resolved transcriptomics of haemocyte discrimination between challenges by nematodes and inert material in the oriental armywormFrontiers in immunology · 2026Article
- Comprehensive transcriptomic analysis reveals immune response modulation inFrontiers in immunology · 2026Article
- Muscling in on immunity: the role of muscle in the insect immune response, demonstrating the value of a whole organism perspective.Frontiers in immunology · 2026Review
- Immunological responses and gut microbial shift of fall armywormFrontiers in microbiology · 2026Article
- Safety Assessment of the Extract of Phycobiliproteins Derived FromAquaculture nutrition · 2026Article
- Comparative transcriptomic analysis of functional and metabolic changes in mass-reared and wildFrontiers in insect science · 2026Article
- Nymphal diets boost adults' immunity via strengthened constitutive immunity and metabolic capacity in Adelphocoris suturalis.Communications biology · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The host defence of insects includes a combination of cellular and humoral responses. The cellular arm of the insect innate immune system includes mechanisms that are directly mediated by haemocytes (e.g., phagocytosis, nodulation and encapsulation). In addition, melanization accompanying coagulation, clot formation and wound healing, nodulation and encapsulation processes leads to the formation of cytotoxic redox-cycling melanin precursors and reactive oxygen and nitrogen species. However, demarcation between cellular and humoral immune reactions as two distinct categories is not straightforward. This is because many humoral factors affect haemocyte functions and haemocytes themselves are an important source of many humoral molecules. There is also a considerable overlap between cellular and humoral immune functions that span from recognition of foreign intruders to clot formation. Here, we review these immune reactions starting with the cellular mechanisms that limit haemolymph loss and participate in wound healing and clot formation and advancing to cellular functions that are critical in restricting pathogen movement and replication. This information is important because it highlights that insect cellular immunity is controlled by a multilayered system, different components of which are activated by different pathogens or during the different stages of the infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.