Evidence map›Paper›PMID 34235409›Full record

ArticleiScience2021

Common features of aging fail to occur in

Arvind Kumar Shukla, Kory Johnson, Edward Giniger

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. The Role of Microbiota inFrontiers in aging · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. The role ofGut microbes
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Arvind Kumar ShuklaNational Institutes of Health, National Institute of Neurological Disorders and Stroke, Bldg 35, Rm 1C 1002, Bethesda, MD 20892, USA.
Kory JohnsonNational Institutes of Health, National Institute of Neurological Disorders and Stroke, Bldg 35, Rm 1C 1002, Bethesda, MD 20892, USA.
Edward GinigerNational Institutes of Health, National Institute of Neurological Disorders and Stroke, Bldg 35, Rm 1C 1002, Bethesda, MD 20892, USA.
National Institutes of Health · US

Funding

Roles of Cdk5 in neurodevelopment and neurodegenerationZIANS003106 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GINIGER, EDWARD · 2009 to 2025
$17.0M
Intramural NIH HHS ZIA NS003106
6 · The paper itself

Abstract

Lifespan is limited both by intrinsic decline in vigor with age and by accumulation of external insults. There exists a general picture of the deficits of aging, one that is reflected in a pattern of age-correlated changes in gene expression conserved across species. Here, however, by comparing gene expression profiling of

Indexed as

Biological sciencesmicrobiologymicrobiomephysiology

Identifiers

PMID34235409
PMCPMC8246586
OpenAlexW3170214784

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.