Evidence map›Paper›PMID 34255145›Full record

ReviewVirchows Archiv : an international journal of pathology2021

Basic principles of biobanking: from biological samples to precision medicine for patients.

Laura Annaratone, Giuseppe De Palma, Giuseppina Bonizzi, Anna Sapino, Gerardo Botti, Enrico Berrino, Chiara Mannelli, Pamela Arcella, Simona Di Martino, Agostino Steffan and 7 more

Open access · hybridAbstract readReview
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 3 pooled it
25.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 3 syntheses or guidelines pooled it, 208 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Biobanked Liver Organoids: A Roadmap for Precision Hepatology.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Establishing a Cervical Cytology Biorepository: A Protocol for Advancing Translational Cervical Cancer Research through Biobanking.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 2 countries.

Laura AnnaratoneCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Giuseppe De PalmaInstitutional BioBank, Experimental Oncology and Biobank Management Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Giuseppina BonizziUnit of Histopathology and Molecular Diagnostics, Division of Pathology and Laboratory Medicine, IEO, European Institute of Oncology, IRCCS, Milan, Italy.
Anna SapinoCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Gerardo BottiIstituto Nazionale Tumori, Fondazione G. Pascale, IRCCS, Naples, Italy.
Enrico BerrinoCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Chiara MannelliCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Pamela ArcellaDepartment of Oncology, University of Turin, Turin, Italy.
Simona Di MartinoDepartment of Pathology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Agostino SteffanImmunopathology and Cancer Biomarkers, IRCCS CRO Aviano-National Cancer Institute, Aviano, Italy.
Maria Grazia DaidoneFondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Vincenzo CanzonieriDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Barbara ParodiIRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Angelo Virgilio ParadisoInstitutional BioBank, Experimental Oncology and Biobank Management Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Massimo BarberisUnit of Histopathology and Molecular Diagnostics, Division of Pathology and Laboratory Medicine, IEO, European Institute of Oncology, IRCCS, Milan, Italy.
Caterina MarchiòCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy. caterina.marchio@unito.it.ORCID http://orcid.org/0000-0003-2024-6131
Alleanza Contro il Cancro (ACC) Pathology and Biobanking Working Group
Candiolo Cancer Institute · ITEuropean Institute of Oncology · ITIstituto Tumori Bari · ITCentro di Riferimento Oncologico · ITDepartment of Medical Sciences · BYFondazione IRCCS Istituto Nazionale dei Tumori · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITOspedale Policlinico San Martino · ITUniversity of Trieste · ITUniversity of Turin · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 21091Horizon 2020 Framework Programme SPIDIA4P (contract no. 733112)Ministero della Salute Ricerca Corrente 2019 ACC
6 · The paper itself

Abstract

The term "biobanking" is often misapplied to any collection of human biological materials (biospecimens) regardless of requirements related to ethical and legal issues or the standardization of different processes involved in tissue collection. A proper definition of biobanks is large collections of biospecimens linked to relevant personal and health information (health records, family history, lifestyle, genetic information) that are held predominantly for use in health and medical research. In addition, the International Organization for Standardization, in illustrating the requirements for biobanking (ISO 20387:2018), stresses the concept of biobanks being legal entities driving the process of acquisition and storage together with some or all of the activities related to collection, preparation, preservation, testing, analysing and distributing defined biological material as well as related information and data. In this review article, we aim to discuss the basic principles of biobanking, spanning from definitions to classification systems, standardization processes and documents, sustainability and ethical and legal requirements. We also deal with emerging specimens that are currently being generated and shaping the so-called next-generation biobanking, and we provide pragmatic examples of cancer-associated biobanking by discussing the process behind the construction of a biobank and the infrastructures supporting the implementation of biobanking in scientific research.

Indexed as

Biological Specimen BanksBiomedical ResearchPrecision MedicineSpecimen HandlingAccreditationGuidelines as TopicHumansPolicy MakingStakeholder ParticipationTerminology as TopicBiobankingBiospecimensCell linesPreanalytical phaseStandardizationTissue specimens

Identifiers

PMID34255145
PMCPMC8275637
OpenAlexW3179831752

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.