Evidence map›Paper›PMID 34255283›Full record

ArticleStem cell reviews and reports2021

The Brain: Is it a Next Frontier to Better Understand the Regulation and Control of Hematopoiesis for Future Modulation and Treatment?

Hal E Broxmeyer, Karmen K Yoder, Yu-Chien Wu, Gary D Hutchins, Scott H Cooper, Sherif S Farag

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell reviews and reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hal E BroxmeyerDepartment of Microbiology and Immunology, Indiana University School of Medicine, 950 West Walnut Street, R2 Bldg, Room 302, Indianapolis, IN, 46202-5181, USA. hbroxmey@iupui.edu.
Karmen K YoderDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Yu-Chien WuDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Gary D HutchinsDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Scott H CooperDepartment of Microbiology and Immunology, Indiana University School of Medicine, 950 West Walnut Street, R2 Bldg, Room 302, Indianapolis, IN, 46202-5181, USA.
Sherif S FaragDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.

Funding

Project-005U54DK106846 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Reuben Kapur, Karen Elizabeth Pollok · 2015 to 2026
$9.7M
Controlling Influences of Oxygen Tension and CD26/DPP4 Enzymatic Activity on Regulation of Hematopoietic Stem/Progenitor Cells and Hematopoiesis During Health, Ageing, and DiseaseR35HL139599 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI BROXMEYER, HAL E. · 2018 to 2021
$3.1M
NHLBI NIH HHS R35 HL139599NIDDK NIH HHS U54 DK106846
6 · The paper itself

Abstract

We wish to suggest the possibility there is a link between the brain and hematopoiesis in the bone marrow and that in the future it may be possible to use such information for better understanding of the regulation of hematopoiesis, and for efficacious treatment of hematopoietic disorders.

Indexed as

Bone MarrowBrainHematopoiesisHumansBrainBrain ImagingHematopoiesisHematopoietic Stem and Progenitor CellsMicroenvironmentNeuronsNeuroTransmitter

Identifiers

PMID34255283
PMCPMC10784999

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.