Evidence map›Paper›PMID 34258299›Full record

Observational studyJournal of immunology research2021

Serum CD4 Is Associated with the Infiltration of CD4

Qi You, Tianyi Fang, Xin Yin, Yimin Wang, Yongheng Yang, Lei Zhang, Yingwei Xue

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qi You *Department of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150086, China.
Tianyi Fang *Department of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150086, China.ORCID https://orcid.org/0000-0002-5015-4898
Xin YinDepartment of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150086, China.ORCID https://orcid.org/0000-0003-3587-371X
Yimin WangDepartment of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150086, China.
Yongheng YangDepartment of Pathology, Harbin Medical University, Harbin, Heilongjiang 150001, China.ORCID https://orcid.org/0000-0002-5637-6643
Lei ZhangDepartment of Pathology, Harbin Medical University, Harbin, Heilongjiang 150001, China.ORCID https://orcid.org/0000-0002-0280-7081
Yingwei XueDepartment of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150086, China.ORCID https://orcid.org/0000-0002-8683-4609
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum CD4, CD8, and CD19 are markers of systemic inflammation. However, there is little evidence on the influence of inflammation on the tumor microenvironment and the prognostic indicators of gastric cancer (GC). In this study, two hundred and eight patients who underwent radical gastrectomy for GC were included. Preoperative peripheral blood samples were used to analyze Serum CD4, CD8, and CD19. The optimal cutoff levels for CD4, CD8, and CD19 were defined by receiver operating characteristic curve analysis (CD4 = 38.85%, CD8 = 14.35%, and CD19 = 7.40%). The areas with specific CD4

Indexed as

AgedAntigens, CD19Biomarkers, TumorCD4 AntigensCD4-Positive T-LymphocytesCD8 AntigensFemaleFollow-Up StudiesGastrectomyGastric MucosaHumansKaplan-Meier EstimateLymphocytes, Tumor-InfiltratingMalePrognosisStomach NeoplasmsAntigens, CD19Biomarkers, TumorCD19 molecule, humanCD4 AntigensCD8 Antigens

Identifiers

PMID34258299
PMCPMC8246328
OpenAlexW3134558074

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.