Evidence mapPaperPMID 34260554Full record

Observational studyMedicine2021

Cardiovascular disease and prevention among people living with HIV in South Florida.

Fahim Pyarali, Roumen Iordanov, Bertrand Ebner, Jelani Grant, Louis Vincent, Alexander Toirac, Tahir Haque, Gerardo Zablah, Kunal Kapoor, Alexis Powell and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Fahim PyaraliDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Roumen IordanovDepartment of Infectious Diseases, Baylor College of Medicine, Houston, TX.ORCID 0000-0002-7554-4737
Bertrand EbnerDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Jelani GrantDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Louis VincentDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Alexander ToiracDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Tahir HaqueDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Gerardo ZablahDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Kunal KapoorDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Alexis PowellDepartment of Infectious Diseases.
Catherine BoulangerDepartment of Infectious Diseases.
Barry HurwitzDepartment of Psychology.
Maria AlcaideDepartment of Infectious Diseases.
Claudia MartinezDepartment of Cardiology, University of Miami Miller School of Medicine, Miami, FL.
University of Miami · USBaylor College of Medicine · US

Funding

Population Engagement CoreP30AI073961 · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2025 to 2025
$1.5M
Miami Center for AIDS Research P30AI073961NIAID NIH HHS P30 AI073961
6 · The paper itself

Abstract

abstractAntiretroviral therapy (ART) has improved survival of patients living with HIV (PLWH); however, this has been accompanied by an increase in cardiovascular disease (CVD). Although preventative measures for CVD among the general population are well described, information is limited about CVD prevention among PLWH. The goal of this study was to characterize the prevalence of CVD in our population and to assess the use of primary and secondary prevention.We performed a retrospective review of PLWH receiving primary care at a large academic center in Miami, Florida. We characterized the prevalence of CVD, CVD risk, and the use of aspirin and statins for primary and secondary CVD prevention.A total of 985 charts were reviewed (45% women, 55% men). Average age was 52.2 years. Average CD4 count was 568 cells/microL. 92.9% were receiving ART, and 71% were virologically suppressed. The median 10-year ASCVD risk was 7.3%. The prevalence of CVD was 10.4% (N = 102). The odds of having CVD was lower in patients on ART (OR 0.47, 95% CI: 0.25-0.90, P = .02). The use of medications for primary and secondary prevention of CVD based on current guidelines was low: 15% and 37% for aspirin respectively, and 25% and 44% for statins.CVD risk and rates of CVD are high among PLWH and receiving ART could protect against CVD. However, the use of medications for primary and secondary prevention is low. Increased awareness of CVD risk-reduction strategies is needed among providers of PLWH to decrease the burden of CVD.

Indexed as

AdultAgedAged, 80 and overAspirinCardiovascular DiseasesFemaleFloridaHeart Disease Risk FactorsHIV InfectionsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedRetrospective StudiesRisk FactorsYoung AdultAspirinHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID34260554
PMCPMC8284739
OpenAlexW3177758008

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.