SynthesisBMJ (Clinical research ed.)2021

Associations between statins and adverse events in primary prevention of cardiovascular disease: systematic review with pairwise, network, and dose-response meta-analyses.

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

+6%+1% to +13%

Bigger than 1 in 10 on the map

As reported

OR 1.06, 95% CI 1.01–1.13

Correlation, not cause

+15.0+1.00 to +29.0

As reported

difference 15, 95% CI 1.00–29.0

the abstract, start to end

… muscle symptoms (21 trials, odds ratio 1.06 (95% confidence interval 1.01 to 1.13); absolute risk difference 15 (95% confidence interval 1 to …

← favours treatmentfavours comparator →

could be chance

Kidney outcomes

OR 1.061.01–1.13

Kidney outcomes

151.00–29.0

StatinsKidney outcomes

1 / 3

2021

…

2022

2023

2024

2025

2026

this paperpooled ittrialcites it