ReviewResearch and reports in tropical medicine2021
A Review on Human Orf: A Neglected Viral Zoonosis.
Review in Research and reports in tropical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 53 citations in OpenAlex.
- Host-Orf virus interactions: A comprehensive review of pathogenesis and immune evasion mechanisms.Virulence · 2026Review
- Article
- Isolation and whole-genome characterization of an Orf virus strain from a goat in Binzhou, Shandong Province, China.Archives of virology · 2026Article
- Genomic characterization of the first goat-associated orf virus genome sequenced directly from a human clinical sample in Portugal.Archives of virology · 2026Article
- Expression of Orf Virus B2L Protein and Monoclonal Antibody Preparation.Microorganisms · 2026Article
- First identification of orf virus from an outbreak of contagious ecthyma in Polish sheep.Journal of veterinary research · 2026Article
- Article
- Molecular Detection and Characterization of Orf Virus in Goats With Clinical Signs From Four Districts of Tanzania.Veterinary medicine and science · 2026Article
- Unravelling the Evolutionary Complexity of Orf Virus: A Global and Multi-Host Perspective.Viruses · 2026Article
- A novel ORF127/ORF130 gene deletion Orf virus vaccine candidate: construction and evaluation.Virology journal · 2026Article
- The Treatment of Contagious Ecthyma in Lambs with a Local Anaesthetic/Antiseptic Wound Formulation Lowers Serum Amyloid A Responses.Animals : an open access journal from MDPI · 2025Article
- Infectivity of Parapoxvirus Orf after 35 Years of Refrigeration.Current microbiology · 2025Article
- Antibody-dependent enhancement of ORFV uptake into host cells.Virulence · 2025Article
- Development and application of a novel indirect ELISA based on recombinant ORFV114 protein for serodiagnosis of Orf virus in goats.Veterinary research communications · 2025Article
- The whole genome analysis of the wild-type and attenuated orf virus reveals that ORF022 facilitates viral replication.BMC genomics · 2025Article
- Three Cases of Adolescent Orf Virus Skin and Soft Tissue Infection in Southeast Texas.The Pediatric infectious disease journal · 2025Article
- Important Diseases of Small Ruminants in Sub-Saharan Africa: A Review with a Focus on Current Strategies for Treatment and Control in Smallholder Systems.Animals : an open access journal from MDPI · 2025Review
- [Orf virus infection in a 53-year-old woman].Dermatologie (Heidelberg, Germany) · 2025Article
- Novel insights into ORFV B2L DNA vaccine-mediated gut microbiota modulation and immune augmentation in rats.Frontiers in immunology · 2025Article
- The identification and genetic characteristics of the Orf virus strain (ORFV-CL24) isolated from Jilin province, China.Frontiers in microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orf virus (ORFV) is the etiologic agent of Orf or ecthyma contagiosum in humans but primarily affects different domestic and wild animals. The disease mostly affects sheep, goats and other small wild ruminants and spreads to humans through direct contact with infected animals or by way of contaminated fomites worldwide. ORFV is taxonomically classified as a member of the genus Parapoxvirus. It is known to have tolerance to inactivation in a drier environment, and it has been recovered from crusts after several months to years. Among immunocompetent people, the lesions usually resolve by its natural course within a maximum of 8 weeks. In immunosuppressed patients, however, it needs the use of various approaches including antiviral, immune modifier or minor surgical excisions. The virus through its association with divergent host ranges helps to develop a mechanism to evade the immune system. The relative emergence of Orf, diagnosed on clinical ground among human cases, in unusual frequencies in southwest Ethiopia between October 2019 and May 2020, was the driver to write this review. The objective was to increase health care providers' diagnostic curiosity and to bring the attentiveness of public health advisors for prevention, control and the development of schemes for surveillance of Orf zoonosis in a similar setting like Ethiopia.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.