Evidence map›Paper›PMID 34267759›Full record

ArticleFrontiers in immunology2021

Survival and Functional Immune Reconstitution After Haploidentical Stem Cell Transplantation in

Ruth Pia Duecker, Lucia Gronau, Patrick C Baer, Stefan Zielen, Ralf Schubert

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ruth Pia DueckerDivision for Allergy, Pneumology and Cystic Fibrosis, Department for Children and Adolescence, Goethe-University, Frankfurt am Main, Germany.
Lucia GronauDivision for Allergy, Pneumology and Cystic Fibrosis, Department for Children and Adolescence, Goethe-University, Frankfurt am Main, Germany.
Patrick C BaerDivision of Nephrology, Department of Internal Medicine III, Goethe-University, Frankfurt am Main, Germany.
Stefan ZielenDivision for Allergy, Pneumology and Cystic Fibrosis, Department for Children and Adolescence, Goethe-University, Frankfurt am Main, Germany.
Ralf SchubertDivision for Allergy, Pneumology and Cystic Fibrosis, Department for Children and Adolescence, Goethe-University, Frankfurt am Main, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic stem cell transplantation (HSCT) has been proposed as a promising therapeutic opportunity to improve immunity and prevent hematologic malignancies in Ataxia-telangiectasia (A-T). However, experience in the transplantation strategy for A-T patients is still scarce. The aim of this study was to investigate whether different approaches of HSCT are feasible in regard to graft versus host response and sufficient concerning functional immune reconstitution.

Indexed as

Immune ReconstitutionAnimalsAtaxia Telangiectasia Mutated ProteinsCD4-Positive T-LymphocytesCell ProliferationCells, CulturedGraft vs Host DiseaseHematopoietic Stem Cell TransplantationImmunologic MemoryLymphocyte ActivationLymphomaMiceMice, KnockoutProof of Concept StudyThymus NeoplasmsTransplantation ChimeraAtaxia Telangiectasia Mutated ProteinsAtm protein, mouseAtaxia-telangiectasiaATMGvHDhaploidenticalHSCTT-lymphocytes

Identifiers

PMID34267759
PMCPMC8276263
OpenAlexW3175732372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.