Evidence map›Paper›PMID 34269175›Full record

SynthesisEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2021

Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021.

Thomas Harder, Judith Koch, Sabine Vygen-Bonnet, Wiebe Külper-Schiek, Antonia Pilic, Sarah Reda, Stefan Scholz, Ole Wichmann

Abstract readSystematic Review
In one paragraph

Synthesis in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  4. Efficacy and safety of COVID-19 vaccines.The Cochrane database of systematic reviews · 2022
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Thomas HarderRobert Koch Institute, Berlin, Germany.
Judith KochRobert Koch Institute, Berlin, Germany.
Sabine Vygen-BonnetRobert Koch Institute, Berlin, Germany.
Wiebe Külper-SchiekRobert Koch Institute, Berlin, Germany.
Antonia PilicRobert Koch Institute, Berlin, Germany.
Sarah RedaRobert Koch Institute, Berlin, Germany.
Stefan ScholzRobert Koch Institute, Berlin, Germany.
Ole WichmannRobert Koch Institute, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on COVID-19 vaccine efficacy/effectiveness (VE) in preventing asymptomatic SARS-CoV-2 infections is needed to guide public health recommendations for vaccinated people. We report interim results of a living systematic review. We identified a total of 30 studies that investigated VE against symptomatic and/or asymptomatic infection. In fully vaccinated individuals, VE against symptomatic and asymptomatic infections was 80-90% in nearly all studies. Fully vaccinated persons are less likely to become infected and contribute to transmission.

Indexed as

COVID-19COVID-19 VaccinesAsymptomatic InfectionsHumansSARS-CoV-2COVID-19 VaccinesCOVID-19SARS-CoV-2systematic reviewvaccinationvaccine effectiveness

Identifiers

PMID34269175
PMCPMC8284046

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.