Evidence map›Paper›PMID 34272439›Full record

ArticleScientific reports2021

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank.

Heidi Foo, Anbupalam Thalamuthu, Jiyang Jiang, Forrest C Koch, Karen A Mather, Wei Wen, Perminder S Sachdev

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Heidi FooCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia. heidi.foo@student.unsw.edu.au.ORCID 0000-0003-0299-9594
Anbupalam ThalamuthuCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia.
Jiyang JiangCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia.
Forrest C KochCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia.
Karen A MatherCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia.
Wei WenCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia.
Perminder S SachdevCentre for Healthy Brain Aging, CHeBA, School of Psychiatry, University of New South Wales Medicine, Kensington, Sydney, NSW, 2052, Australia.
UNSW Sydney · AU

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

Here, we investigated the genetics of weighted functional brain network graph theory measures from 18,445 participants of the UK Biobank (44-80 years). The eighteen measures studied showed low heritability (mean h

Indexed as

Genetic VariationInheritance PatternsPolymorphism, Single NucleotideQuantitative Trait, HeritableAgedBiological Specimen BanksBrainBrain MappingFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansMaleMiddle AgedModels, Genetic

Identifiers

PMID34272439
PMCPMC8285376
OpenAlexW3179813350

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.