Evidence map›Paper›PMID 34276708›Full record

ReviewFrontiers in immunology2021

Underwhelming or Misunderstood? Genetic Variability of Pattern Recognition Receptors in Immune Responses and Resistance to

Jean-Yves Dubé, Vinicius M Fava, Erwin Schurr, Marcel A Behr

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Phenotypic adaptation ofFrontiers in cellular and infection microbiology · 2022
    Review
  11. Mice Dually Disrupted forFrontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jean-Yves DubéDepartment of Microbiology and Immunology, McGill University, Montreal, QC, Canada.
Vinicius M FavaProgram in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
Erwin SchurrDepartment of Microbiology and Immunology, McGill University, Montreal, QC, Canada.
Marcel A BehrDepartment of Microbiology and Immunology, McGill University, Montreal, QC, Canada.
McGill University · CAMcGill University Health Centre · CA

Funding

Human genetics of TB resistance in HIV-infected personsR01AI124349 · NIAID · MCGILL UNIVERSITY HEALTH CTR RES INST · PI SCHURR, ERWIN · 2016 to 2020
$8.0M
CIHR FDN-143332CIHR FDN-148362NIAID NIH HHS R01 AI124349
6 · The paper itself

Abstract

Human genetic control is thought to affect a considerable part of the outcome of infection with

Indexed as

Genetic Predisposition to DiseaseGenetic VariationAnimalsBiomarkersDisease ResistanceHost-Pathogen InteractionsHumansImmunityLectins, C-TypeMiceMice, KnockoutMycobacterium tuberculosisReceptors, Pattern RecognitionTuberculosisBiomarkersLectins, C-TypeReceptors, Pattern RecognitionC-type lectin receptors (CLRs)genetic association studies (GAS)microbe associated molecular pattern (MAMP)mycobacterium tuberculosisNOD-like receptors (NLRs)pattern recognition receptor (PRR)toll-like receptors (TLR)tuberculosis

Identifiers

PMID34276708
PMCPMC8278570
OpenAlexW3174912361

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.