Evidence map›Paper›PMID 34282934›Full record

ArticlemSystems2021

Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.

Wei Fan, Hui Kan, Hai-Yan Liu, Tian-Lei Wang, Yi-Ning He, Miao Zhang, Ya-Xin Li, Yi-Jie Li, Wei Meng, Qing Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
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  4. Review
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  14. Microbiome-associated human genetic variants impact phenome-wide disease risk.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Article
  17. Heritable Tissue-Specific Gene Expression Associates With Chronic Wound Microbial Species.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Wei Fan *Department of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Hui Kan *Department of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Hai-Yan Liu *Department of Clinical Laboratory, Anqing Municipal Hospital, Anqing, China.
Tian-Lei WangDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Yi-Ning HeDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Miao ZhangDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Ya-Xin LiDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Yi-Jie LiDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Wei MengDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Qing LiDepartment of Obstetrics and Gynecology, Anqing Municipal Hospital, Anqing, China.
An-Qun HuDepartment of Clinical Laboratory, Anqing Municipal Hospital, Anqing, China.
Ying-Jie ZhengDepartment of Epidemiology, Fudan Universitygrid.8547.e, Shanghai, China.
Fudan University · CNAnqing City Hospital · CN

Funding

National Natural Science Foundation of China (NSFC) 81373065 81773490
6 · The paper itself

Abstract

The influence of human genetic variants on the vaginal bacterial traits (VBTs) of pregnant women is still unknown. Using a genome-wide association approach based on the 16S rRNA bacteriome analysis, a total of 72 host genetic variant (single nucleotide polymorphisms [SNPs], indels, or copy number variations [CNVs])-VBT associations were found that reached the genome-wide significance level (

Indexed as

16S ampliconbacteriomegenetic variantsmicrobiomepregnant womenvaginal bacterial traits

Identifiers

PMID34282934
PMCPMC8407429
OpenAlexW3183368020

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.