ArticleClinical interventions in aging2021
Association Between Physical Performance and Cognitive Function in Chinese Community-Dwelling Older Adults: Serial Mediation of Malnutrition and Depression.
Article in Clinical interventions in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 44 citations in OpenAlex.
- Mind, Mood, and Mobility: Rethinking Functional Disability Prevention in Older Adults on the Basis of a Longitudinal Cohort From CHARLS.Journal of the American Heart Association · 2026Article
- The health outcomes of shelter and settlements interventions in humanitarian crises: a systematic review.Conflict and health · 2026Review
- Mapping Social and Physical Frailty in the Peruvian Amazon: Associated Factors Among Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- An L-shaped association between prognostic nutritional index and all-cause mortality among adults with depressive symptoms: a cohort study using NHANES 2005-2018.BMC psychiatry · 2026Article
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- Combined effect of living alone and osteoporosis status on the prevalence of depression in Chinese community-dwelling older population: a cross-sectional study.Frontiers in public health · 2026Article
- Nutritional status mediates the relationship between depression and mild cognitive impairment among Chinese community-dwelling older adults.Frontiers in psychiatry · 2026Article
- The association between nutritional status, sarcopenia, and depressive symptoms in elderly Chinese patients receiving maintenance hemodialysis: a hospital-based cross-sectional study.Frontiers in nutrition · 2026Article
- Association Between Physical Performance and Depressive Symptoms in Older Adults: A Retrospective Cross-Sectional Study.Clinical interventions in aging · 2026Article
- Examination of the healthy aging center data.BMC geriatrics · 2025Observational
- Longitudinal Trajectories of Cognitive Function Among Chinese Middle-Aged and Older Adults: The Role of Sarcopenia and Depressive Symptoms.Brain sciences · 2025Article
- Unraveling the link between physical activity and cognitive function: the mediating impact of depressive symptoms.BMC public health · 2025Article
- Inequalities in Mild Cognitive Impairment Risk Among Chinese Middle-Aged and Older Adults: Insights from an Integrated Learning Model.Risk management and healthcare policy · 2025Article
- The Mediating Role of Cognitive Function in the Relationship Between Physical Performance and Depressive Symptoms Among Older Adults in China: A Prospective Longitudinal Study.Nursing research and practice · 2025Article
- The influence of healthy eating index on cognitive function in older adults: chain mediation by psychological balance and depressive symptoms.BMC geriatrics · 2024Article
- An analysis of factors influencing cognitive dysfunction among older adults in Northwest China based on logistic regression and decision tree modelling.BMC geriatrics · 2024Article
- Study on plasma metabolomics profiling of depression in Chinese community-dwelling older adults based on untargeted LC/GC‒MS.Scientific reports · 2024Article
- The Mediating Role of Psychological Balance on the Effects of Dietary Behavior on Cognitive Impairment in Chinese Elderly.Nutrients · 2024Article
- Sex differences in the combined influence of inflammation and nutrition status on depressive symptoms: insights from NHANES.Frontiers in nutrition · 2024Article
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to propose a serial mediational model to further analyze the relationship between poor physical performance, malnutrition, depression and cognitive impairment in Chinese community-dwelling older adults. PATIENTS AND
methodsThis study consisted of 1386 community-dwelling Chinese older adults aged 65 years and older in Shanghai, China. Mild cognitive impairment (MCI) was assessed by the Mini-Mental State Examination (MMSE) and Instrumental Activities Of Daily Living (IADL). Physical performance was assessed by short physical performance battery (SPPB). Malnutrition was defined with the Mini Nutritional Assessment (MNA). Depressive symptoms were evaluated by the 30-item Geriatric Depression Scale (GDS). Serial multiple mediator models were used.
resultsThe mean age of the final analysis sample was 73.62±6.14, and 57.6% (n=809) were females. The prevalence of MCI was 14.35% (n=199). Physical performance (p<0.001), nutritional status (p=0.025), and depressive symptoms (p=0.002) were correlated with MCI. The serial mediational model revealed that MNA and GDS scores significantly mediated association of SPPB and MMSE scores (c'=0.4728, p<0.001). Furthermore, depressive symptoms significantly mediated the association of physical performance and cognition (p=0.0311), while malnutrition had no independent mediating effect between these two factors (p=0.794).
conclusionOur study examined the serial multiple mediation roles of nutritional status and depressive symptoms on the relationship between physical performance and cognitive function in community-dwelling Chinese older adults. Older adults who were in poor physical condition tend to have worse nutritional status, more severe depression, and poorer cognitive function.
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