Evidence map›Paper›PMID 34290863›Full record

Trial reportJournal of nutritional science2021

Postprandial effects of a whey protein-based multi-ingredient nutritional drink compared with a normal breakfast on glucose, insulin, and active GLP-1 response among type 2 diabetic subjects: a crossover randomised controlled trial.

Pimnapanut Sridonpai, Aree Prachansuwan, Kemika Praengam, Siriporn Tuntipopipat, Wantanee Kriengsinyos

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of nutritional science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Manipulation of Post-Prandial Hyperglycaemia in Type 2 Diabetes: An Update for Practitioners.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pimnapanut SridonpaiInstitute of Nutrition, Mahidol University, Nakhon Pathom, Thailand.
Aree PrachansuwanInstitute of Nutrition, Mahidol University, Nakhon Pathom, Thailand.
Kemika PraengamInstitute of Nutrition, Mahidol University, Nakhon Pathom, Thailand.
Siriporn TuntipopipatInstitute of Nutrition, Mahidol University, Nakhon Pathom, Thailand.
Wantanee KriengsinyosInstitute of Nutrition, Mahidol University, Nakhon Pathom, Thailand.
Mahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postprandial hyperglycaemia is recognised as an important target in type 2 diabetes management. Dietary pattern, meal composition, and amount of food intake are major factors for maintaining postprandial blood glucose levels. The aim of this study was to investigate the effect of consuming a whey protein-based multi-ingredient nutritional drink (WD) on postprandial glycaemic, insulinaemic, and active glucagon-like peptide-1 (GLP-1) responses in comparison to a typical breakfast, which is boiled white rice with chicken (BC) in patients with type 2 diabetes mellitus (T2DM). Fifteen subjects with T2DM participated in a randomised, controlled, cross-over study. Two isocaloric diets with similar nutrient composition were randomly tested with at least 7 d in between. Glucose, insulin, and active GLP-1 were measured by standard methods with blood samples collected with a venous catheter for 240 min during a kinetic test. The incremental area under the curve (iAUC

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2InsulinBreakfastCross-Over StudiesGlucagon-Like Peptide 1HumansPostprandial PeriodWhey ProteinsBlood GlucoseGlucagon-Like Peptide 1InsulinWhey ProteinsAcute glycaemic responseBC, boiled white rice with chickenBMI, body mass indexBreakfast mealGLP-1, glucagon-like peptide-1Glucagon-like peptide-1iAUC, incremental area under the curvemin, minutesem, standard error of the meanT2DM, type 2 diabetes mellitusWD, whey protein-based multi-ingredient nutritional drinkWhey proteinXylitol

Identifiers

PMID34290863
PMCPMC8278161
OpenAlexW3184089448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.