Evidence map›Paper›PMID 34291559›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2021

Evaluation of serum calcium differences in hypertensive crises and control patients: A randomly matched case-control study.

IfeanyiChukwu O Onor, Rose M Duchane, Casey J Payne, Hannah Naquin Lambert, DeMaurian M Mitchner, Robbie A Beyl, Anh T Nguyen, Sarah E Bilbe, Andrea Arriaga White, Mariah W Johnson and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

IfeanyiChukwu O OnorCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.ORCID 0000-0002-8005-8602
Rose M DuchaneCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Casey J PayneCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Hannah Naquin LambertCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
DeMaurian M MitchnerCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Robbie A BeylPennington Biomedical Research Center, Baton Rouge, LA, USA.
Anh T NguyenCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Sarah E BilbeCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Andrea Arriaga WhiteCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Mariah W JohnsonCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Amber I FacianeCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Emmanuel KouagouCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Stephanie A HymelCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Bria M WatesCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Asia D SandersCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Phillip C B VoCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Jordan D BatesCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Raven J SpoonerCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Christopher J GillardCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
John I OkogbaaCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Daniel F SarpongCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Rim M HadguMidwestern University College of Pharmacy - Glendale, Glendale, AZ, USA.
Samuel C OkpechiDepartment of Biochemistry and Molecular Biology, School of Medicine and Health Sciences Center, Louisiana State University, New Orleans, LA, USA.
Gabriel I OnorWarren Alpert Medical School, Brown University, Providence, RI, USA.
Michael C OkoronkwoDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
Mihran V NaljayanDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
Shane G GuilloryDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
Shane E SanneDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
CardioRenal Research Group (CRRG)

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Xavier RCMI Renewal Application-Research Infrastructure CoreU54MD007595 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI Guangdi Wang, Christopher Williams · 2019 to 2026
$41.9M
Xavier Pharmacy Endowment For Minority HealthS21MD000100 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI FRANCIS, NORMAN C. · 2001 to 2011
$39.0M
Xavier's RCMI Cancer Research ProgramG12MD007595 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI D'AMOUR, GENE · 2012 to 2018
$15.7M
HRSA HHS D34HP00006NIGMS NIH HHS 1 U54 GM104940NIGMS NIH HHS 2U54GM104940-02NIGMS NIH HHS U54 GM104940NIMHD NIH HHS 2U54MD007595-11NIMHD NIH HHS 5G12MD007595NIMHD NIH HHS 5 S21 MD 000100-12NIMHD NIH HHS G12 MD007595NIMHD NIH HHS S21 MD000100NIMHD NIH HHS U54 MD007595
6 · The paper itself

Abstract

The role of calcium in blood pressure has been widely studied among hypertensive patients; however, no study has explored the role of calcium in hypertensive crises. The primary objective of this study is to evaluate the differences in serum calcium levels between hypertensive crises patients and a 1:1 random matched controls (age-, sex-, race-, diabetes, and body mass index matched). This study is a single-center, retrospective, chart review, case-control study of patients with hypertensive crises (case group) and patients without hypertensive crises (control group). Patients were included in the case group if they were 18 years of age or older with hypertensive crises and have a documented calcium level. The control group patients were required to be 18 years of age or older, have a documented calcium level, and have no diagnosis of hypertensive crises. The primary outcome of the study was to compare the mean serum calcium in patients with hypertensive crises vs patients without hypertensive crises. Five hundred and sixty-six patients were included in the study: 283 patients in both the case group and control group. The primary outcome results showed that serum calcium concentration was not significantly different between the case group (8.99 ± 0.78 mg/dL) and control group (8.96 ± 0.75 mg/dL) (P = .606). This study found no significant difference in serum calcium levels in patients with hypertensive crises compared to a random matched control group. Larger observational or experimental studies may be useful to evaluate the effect of calcium on blood pressure in hypertensive crises.

Indexed as

CalciumHypertensionAdolescentAdultBlood PressureCase-Control StudiesHumansRetrospective StudiesCalciumcalciumhypertension-generalhypertensive crisesmagnesiumphosphorus

Identifiers

PMID34291559
PMCPMC8635273

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.