Evidence map›Paper›PMID 34296307›Full record

ReviewMolecular medicine reports2021

Ghrelin and its role in gastrointestinal tract tumors (Review).

Irene Alexandra Spiridon, Delia Gabriela Apostol Ciobanu, Simona Eliza Giușcă, Irina Draga Căruntu

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Genome-Wide Association and Two-Sample Mendelian Randomization Analyses of Plasma Ghrelin and Gastrointestinal Cancer Risk.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Role of the Ghrelin System in Colorectal Cancer.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Irene Alexandra SpiridonDepartment of Pathology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași 700115, Romania.
Delia Gabriela Apostol CiobanuDepartment of Pathology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași 700115, Romania.
Simona Eliza GiușcăDepartment of Pathology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași 700115, Romania.
Irina Draga CăruntuDepartment of Histology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași 700115, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ghrelin, an orexigenic hormone, is a peptide that binds to the growth hormone secretagogue receptor; it is secreted mainly by enteroendocrine cells in the oxyntic glands of the stomach. Ghrelin serves a role in both local and systemic physiological processes, and is implicated in various pathologies, including neoplasia, with tissue expression in several types of malignancies in both

Indexed as

Gastrointestinal NeoplasmsAnimalsGhrelinHumansMesodermNeuroendocrine TumorsReceptors, GhrelinSignal TransductionGhrelinReceptors, Ghrelincancercarcinogenesisghrelingrowth hormone secretagogue receptorpathologyprognosis

Identifiers

PMID34296307
PMCPMC8335721
OpenAlexW3183159799

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.