Evidence map›Paper›PMID 34298967›Full record

ReviewInternational journal of molecular sciences2021

Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease.

Olivia Wegrzyniak, Maria Rosestedt, Olof Eriksson

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. CAR-macrophage: Breaking new ground in cellular immunotherapy.Frontiers in cell and developmental biology · 2024
    Review
  6. Article
  7. The Emerging Role of Ferroptosis in Liver Diseases.Frontiers in cell and developmental biology · 2021
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olivia WegrzyniakScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, SE-751 83 Uppsala, Sweden.
Maria RosestedtScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, SE-751 83 Uppsala, Sweden.
Olof ErikssonScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, SE-751 83 Uppsala, Sweden.ORCID 0000-0002-2515-8790

Funding

EFSD/Lilly no applicableMagnus Bergvalls Foundation no applicableScience for Life Laboratory no applicablethe Swedish Research Council no applicable
6 · The paper itself

Abstract

Pathological fibrosis of the liver is a landmark feature in chronic liver diseases, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Diagnosis and assessment of progress or treatment efficacy today requires biopsy of the liver, which is a challenge in, e.g., longitudinal interventional studies. Molecular imaging techniques such as positron emission tomography (PET) have the potential to enable minimally invasive assessment of liver fibrosis. This review will summarize and discuss the current status of the development of innovative imaging markers for processes relevant for fibrogenesis in liver, e.g., certain immune cells, activated fibroblasts, and collagen depositions.

Indexed as

AlarminsAnimalsAquaporinsCollagenContrast MediaCytokinesElasticity Imaging TechniquesEndopeptidasesFatty AcidsFibroblast Activation Protein AlphaFibroblastsFluorine RadioisotopesGallium RadioisotopesHepatic Stellate CellsHepatocytesHumansAlarminsAquaporinsCCR2 protein, humanCcr2 protein, mouseCollagenContrast MediaCytokinesEndopeptidasesFatty AcidsFibroblast Activation Protein AlphaFluorine-18Fluorine RadioisotopesGallium-68Gallium RadioisotopesMembrane ProteinsRadiopharmaceuticalsReceptors, CCR2Triglyceridescollagenfibroblastsfibrosisimagingimmune cellsNASHpositron emission tomography

Identifiers

PMID34298967
PMCPMC8306605

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.